Equine/Horse morbillivirus antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Equine/Horse morbillivirus antibodies pairs and antigen for animal health (animal Equine/Horse infectious disease Equine/Horse morbillivirus pneumonia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Equine/Horse disease testing products collection >>

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P148-Ag01	Recombinant Equine/Horse morbillivirus protein	$3090.00
GMP-VT-P148-Ab01	Anti-Equine/Horse morbillivirus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P148-Ab02	Anti-Equine/Horse morbillivirus mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P148-Ag01
Product Name	Recombinant Equine/Horse morbillivirus protein
Pathogen	Equine/Horse morbillivirus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine/Horse morbillivirus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Equine/Horse morbillivirus level test of animal Equine/Horse infectious disease with Equine/Horse morbillivirus pneumonia.
Tag	His
Product description	Recombinant Equine/Horse morbillivirus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P148-Ab01,GMP-VT-P148-Ab02
Pathogen	Equine/Horse morbillivirus
Product Name	Anti-Equine/Horse morbillivirus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine/Horse morbillivirus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine/Horse morbillivirus antibodies in Equine/Horse morbillivirus level test of animal Equine/Horse infectious disease with Equine/Horse morbillivirus pneumonia.
Product description	Anti-Equine/Horse morbillivirus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine/Horse morbillivirus antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Pathogen

Equine Morbillivirus: A Hypothetical Pathogen for Equine Health

Introduction:

Equine Morbillivirus, a theoretical member of the Morbillivirus genus within the Paramyxoviridae family, is a construct designed to simulate the characteristics of a virus that could specifically affect equine hosts, particularly horses (Equus ferus caballus). While this pathogen is hypothetical, a detailed understanding of its theoretical properties may offer insights into the potential challenges and diagnostic strategies in the realm of equine virology.

Pathogen Classification:

Theoretical Pathogen Classification:

Type: Virus

Family: Paramyxoviridae

Genus: Morbillivirus

Pathogen Structure:

Equine Morbillivirus, like other morbilliviruses, is characterized by a single-stranded, negative-sense RNA genome. The viral genome comprises several critical genes and proteins:

Nucleoprotein (N): The N gene encodes the nucleoprotein, essential for encapsidating the viral RNA.

Phosphoprotein (P): The P gene encodes the phosphoprotein, which plays a crucial role in viral replication and transcription.

Matrix protein (M): Encoded by the M gene, this protein contributes to the structure of the virus particle and its assembly.

Fusion protein (F): The F gene encodes the fusion protein, responsible for mediating viral entry into host cells.

Hemagglutinin protein (H): Encoded by the H gene, this protein is pivotal in viral attachment to host cell receptors, facilitating infection.

Large protein (L): The L gene encodes the large protein, responsible for the RNA-dependent RNA polymerase activity, essential for viral replication.

Hosts and Associated Diseases:

Equine Morbillivirus, in our hypothetical scenario, primarily infects horses. The disease caused by this pathogen is referred to as "Equine Morbillivirus Disease." The hypothetical clinical manifestations of this disease might include respiratory symptoms, fever, and other systemic signs, similar to other morbillivirus infections in their respective hosts.

Diagnostic Methods:

In the event of a suspected Equine Morbillivirus infection, veterinarians and researchers would employ various diagnostic methods to identify and confirm the presence of the virus. These methods encompass:

Polymerase Chain Reaction (PCR): PCR is a fundamental tool for the detection of viral nucleic acids. Specific primers designed for Equine Morbillivirus genes, such as H or N, are utilized to amplify viral RNA for identification.

Enzyme-Linked Immunosorbent Assay (ELISA): ELISA tests employ antibodies designed to recognize Equine Morbillivirus proteins, particularly H and F. By binding to these proteins, the presence of the virus can be detected.

Virus Isolation: This technique involves attempts to cultivate and isolate the virus within suitable cell lines. It not only confirms the virus's presence but also provides a sample for further characterization and study.

Serological Tests: Detecting Equine Morbillivirus-specific antibodies in the host's immune response is another crucial diagnostic approach. It indicates exposure to the virus and potential immunity.

Immunohistochemistry: In cases where post-mortem tissue samples are available, immunohistochemistry allows for the identification of viral antigens within tissues. This can provide insights into the pathogenesis of the disease.

Genes/Proteins Targeted in Diagnostic Methods:

The diagnostic methods mentioned above are tailored to target specific Equine Morbillivirus genes and proteins:

Hemagglutinin (H): This protein is a key target in both PCR and ELISA methods due to its essential role in viral attachment and membrane fusion.

Nucleoprotein (N): The N gene and protein are often the focus of PCR-based diagnostics, allowing for the detection of the viral genome.

Fusion (F): The F protein is targeted in ELISA tests to confirm the presence of Equine Morbillivirus.

In conclusion, while Equine Morbillivirus is a hypothetical pathogen, understanding its theoretical properties, diagnostic approaches, and potential impact on equine health can serve as a valuable exercise for researchers and veterinarians in preparing for real-world challenges in equine virology. It underscores the importance of robust diagnostic techniques in managing and controlling potential viral threats to horse populations. Please note that this information is purely hypothetical and should not be considered as representative of any real-world pathogen. For accurate and updated information on actual pathogens, consult authoritative sources and scientific literature.

About GDU