Marek Disease Virus Glycoprotein E antibody and antigen (recombinant protein)

Diagnostic anti-Marek Disease Virus Glycoprotein E antibodies pairs and antigen for animal health (animal Chicken infectious disease Marek's disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P173-Tg001-Ag01 Recombinant Marek Disease Virus Glycoprotein E protein $3090.00
GMP-VT-P173-Tg001-Ab01 Anti-Marek Disease Virus Glycoprotein E mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P173-Tg001-Ab02 Anti-Marek Disease Virus Glycoprotein E mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P173-Tg001-Ab03 Anti-Marek Disease Virus Glycoprotein E human monoclonal antibody (mAb) $3090.00
GMP-VT-P173-Tg001-Ab04 Anti-Marek Disease Virus Glycoprotein E human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P173-Tg001-Ag01
Product Name Recombinant Marek Disease Virus Glycoprotein E protein
Pathogen Marek Disease Virus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Marek Disease Virus Glycoprotein E antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Marek Disease Virus level test of animal Chicken infectious disease with Marek's disease.
Tag His
Product description Recombinant Marek Disease Virus Glycoprotein E proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P173-Tg001-Ab01,GMP-VT-P173-Tg001-Ab02
Pathogen Marek Disease Virus
Product Name Anti-Marek Disease Virus Glycoprotein E mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Marek Disease Virus Glycoprotein E antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Marek Disease Virus antibodies in Marek Disease Virus level test of animal Chicken infectious disease with Marek's disease.
Product description Anti-Marek Disease Virus Glycoprotein E mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Marek Disease Virus antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P173-Tg001-Ab03,GMP-VT-P173-Tg001-Ab04
Pathogen Marek Disease Virus
Product Name Anti-Marek Disease Virus Glycoprotein E human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Marek Disease Virus Glycoprotein E antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Marek Disease Virus antibodies in Marek Disease Virus level test of animal Chicken infectious disease with Marek's disease.
Product description Anti-Marek Disease Virus Glycoprotein E mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen Information


    Avian Marek Disease Virus is a highly contagious virus that primarily infects chickens, although it can also infect other domesticated bird species such as turkeys and quail. This virus is classified as a member of the herpesvirus family, which includes other notable viruses such as the Human Herpes Virus (HHV) and the equine herpesvirus.

    The genome of Avian Marek Disease Virus is composed of a linear, double-stranded DNA molecule that is approximately 180 kilobases in length and harbors approximately 100 genes. One of the key proteins encoded by this genome is the oncoprotein Meq, which plays a role in the development of tumors. Glycoprotein B is another crucial protein that is involved in the viral entry process, helping the virus sample its host cells for the appropriate viral receptors.

    Infected birds can present a range of clinical symptoms upon infection with Avian Marek Disease Virus, including weight loss, paralysis, and tumors. The virus can be transmitted both horizontally and vertically, being passed between birds via feather dander, saliva, and excrement. In some cases, the virus can cause nerve damage and paralysis in infected birds, leading to difficulty walking or standing. In other cases, the virus may lead to the development of lymphomas, or tumors of the lymphatic tissues that can be fatal.

    To diagnose Avian Marek Disease Virus, there are several diagnostic methods available, including PCR, ELISA, and virus isolation. These methods target specific genes and proteins expressed by the virus, such as the Meq oncogene, VP22 protein, and glycoprotein B. PCR is a highly sensitive molecular technique used to detect small amounts of DNA in biological samples, while ELISA is an immunological assay used to detect antibodies against the virus in patient serum or other bodily fluids. Virus isolation can involve growing the virus in cell cultures to confirm its presence within an infected host.

    In terms of treatment and prevention, vaccination is one of the most effective ways to prevent Avian Marek Disease Virus infection. Vaccines can be administered to young birds prior to exposure to the virus, providing them with immunity against the disease. In addition to vaccination, good hygiene practices such as regular cleaning and disinfection of poultry houses can help prevent the spread of the virus between birds.

    In conclusion, Avian Marek Disease Virus is a highly contagious herpesvirus that primarily infects chickens, causing the development of tumors and other clinical symptoms that can be fatal. Diagnosing the virus requires specialized laboratory techniques such as PCR, ELISA, and virus isolation, while vaccination and good hygiene practices can help prevent its transmission and spread.



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