Fight against COVID-19
Diagnostic antibody & antigen
Services
- Custom AAV Production
- Custom Adenovirus Production
- Custom Lentivirus Production
- Pre-made AAV Production
- Pre-made Adenovirus Production
- Pre-made Lentivirus Production
- AAV-LC3 Autophagy Flux Detection
- Ad-LC3 Autophagy Flux Detection
- Lv-LC3 Autophagy Flux Detection
- AAV Control Virus Production
- CRISPR/Cas9 AAV Production
- CRISPR/Cas9 Adenovirus Production
Supports
SOCAIL MEDIA
AAV8-1m vector system (retina-validated AAV expression and packaging plasmids)
AAV protocol Download
AAV User Manual Download
Capsid mutant-AAV serotype 8 variant (AAV8-(Y733F) system - Introduction
GeneMedi's AAV8-1m Vector System (AAV serotype 8 variant(Y733F) helper-free packaging plasmids system) is including AAV8-1m Rep-Cap plamid (AAV8-1m -RC plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).
You can choose your suiltable AAV expression vector plasmids from GeneMedi's AAV expression vector core. The AAV expression vector plasmids were constructed with differernt expression cassettes,containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas9-gRNA AAV expression vector.
AAV8-1m Rep-Cap plamid supplies the AAV8 Rep(replication) proteins and the AAV8-1m capsid-engineered protein.
The tissue tropism of AAV8-1m vector has been validated in retina with higher transduction efficiency and more rapid onset of expression in photoreceptor cells by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
| Product Name | Organization Type | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| AAV8-1m vector system Cat.No.:P-PK10 1. AAV8-1m Rep-Cap plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug |
Academic | 3024 | ||
| AAV8-1m vector system Cat.No.:P-PK10 1. AAV8-1m Rep-Cap plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug |
Industry R&D (excluding CRO&CDMO&CXO) | Inquiry | ||
| AAV8-1m vector system Cat.No.:P-PK10 1. AAV8-1m Rep-Cap plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug Expression vector refers only to B85, if you need other expression vector, please click →AAV Expression Vector list |
CRO&CDMO& CXO&CMC& Manufacturing company |
Inquiry | ||
| Shipping Cost: | 169.00 | |||
| Total: | ||||
AAV8 capsid variant (Y733F) tissue tropism and gene transduction (serotype-specific AAV infection)
The tissue tropism of AAV8-1m vector has been validated in retina with higher transduction efficiency and more rapid onset of expression in photoreceptor cells by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml Cells: HEK-293T MOI: MOI=1×104 Determine assay: 36 hours post infection, immunofluorescence microscopy
Other AAV vector system
