Picture loading failed.

pdf downloadAAV protocol Download
pdf downloadAAV User Manual Download


Capsid mutant-AAV serotype 8 variant (AAV8-(Y733F,Y447F) system - Introduction

GeneMedi's AAV8-2m Vector System (AAV serotype 8 variant(Y733F, Y447F) helper-free packaging plasmids system) is including AAV8-2m Rep-Cap plamid (AAV8-2m -RC plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).

You can choose your suiltable AAV expression vector plasmids from GeneMedi's AAV expression vector core. The AAV expression vector plasmids were constructed with differernt expression cassettes,containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas9-gRNA AAV expression vector.

AAV8-2m Rep-Cap plamid supplies the AAV8 Rep(replication) proteins and the AAV8-2m capsid-engineered protein.

The tissue tropism of AAV8-2m vector has been validated in in Pancreas and retina,with potential applications in tissue-specific gene therapy and cancer therapy.

Product Name Contents Price(In USD) Qty (Quantity) Sum(In USD)
AAV8-2m vector system 1. AAV8 variant(Y733F,Y447F) Rep-Cap plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-3flag-T2A-ZsGreen
(P-AAVV-B01), 5ug
Expression vector default to B01, if you need more expression vector, pleasae click →AAV Expression Vector list
1680
Shipping Cost: 360.00
Total:

AAV8 capsid variant (Y733F, Y447F) tissue tropism and gene transduction
(serotype-specific AAV infection)

The tissue tropism of AAV8-2m vector has been validated in in Pancreas and retina,with potential applications in tissue-specific gene therapy and cancer therapy.

Picture loading failed.
Figure. Selected transduction results of AAV in vitro (in 293T cell line)

Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml
Cells: HEK-293T
MOI: MOI=1×104
Determine assay: 36 hours post infection, immunofluorescence microscopy


Other AAV vector system


AAV1 vector system

AAV2 vector system

AAV2 variant(Y444F) vector system

AAV2 variant (Y272F,Y444F,Y500F,Y730F) vector system

AAV2 variant(Y444F,Y730F,Y500F,Y272F,Y704F,Y252F) vector system

AAV2 variant(AAV2.7m8) vector system

AAV5 vector system

AAV6 vector system

AAV8 vector system

AAV8-1m vector system



AAV8-3m vector system

AAV9 vector system

AAV-Rh10 vector system

AAV-DJ vector system

AAV-Dj8 vector system

AAV2-Retro (Retrograde) vector system

AAV9-PHP.B vector system

AAV9-PHP.eB vector system

AAV9-PHP.S vector system