Fight against COVID-19
Diagnostic antibody & antigen
Services
- Custom AAV Production
- Custom Adenovirus Production
- Custom Lentivirus Production
- Pre-made AAV Production
- Pre-made Adenovirus Production
- Pre-made Lentivirus Production
- AAV-LC3 Autophagy Flux Detection
- Ad-LC3 Autophagy Flux Detection
- Lv-LC3 Autophagy Flux Detection
- AAV Control Virus Production
- CRISPR/Cas9 AAV Production
- CRISPR/Cas9 Adenovirus Production
Supports
SOCAIL MEDIA
AAAV8 variant (Y733F,Y447F,Y275F) vector system
(Pancreas-retina validated AAV expression and packaging plasmid system)
AAV protocol Download AAV User Manual Download Capsid mutant-AAV serotype 8 variant (AAV8-(Y733F,Y447F,Y275F) system-Introduction
GeneMedi's AAV8 variant (Y733F,Y447F,Y275F) Vector System (AAV serotype 8 variant (Y733F,Y447F,Y275F) helper-free packaging plasmids system) is including AAV8 variant (Y733F,Y447F,Y275F) Rep-Cap plamid (AAV8 variant (Y733F,Y447F,Y275F) -RC plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).
You can choose your suiltable AAV expression vector plasmids from GeneMedi's AAV expression vector core. The AAV expression vector plasmids were constructed with differernt expression cassettes,containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas9-gRNA AAV expression vector.
AAV8 variant (Y733F,Y447F,Y275F) Rep-Cap plamid supplies the AAV8 Rep(replication) proteins and the AAV8 variant (Y733F,Y447F,Y275F) capsid-engineered protein.
The tissue tropism of AAV8 variant (Y733F, Y447F, Y275F) vector has been validated in in Pancreas, Pancreatic Tumors and retina,with potential applications in tissue-specific gene therapy and cancer therapy.
| Product Name | Organization Type | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| AAV8 variant (Y733F, Y447F, Y275F) vector system Cat.No.:P-PK12 1. AAV8 variant(Y733F,Y447F, Y275) Rep-Cap plasmid, 5ug2. AAV Helper Plasmid, 5ug3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Academic | 3024 | ||
| AAV8 variant (Y733F, Y447F, Y275F) vector system Cat.No.:P-PK12 1. AAV8 variant(Y733F,Y447F, Y275) Rep-Cap plasmid, 5ug2. AAV Helper Plasmid, 5ug3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Industry R&D (excluding CRO&CDMO&CXO) | Inquiry | ||
| AAV8 variant (Y733F, Y447F, Y275F) vector system Cat.No.:P-PK12 1. AAV8 variant(Y733F,Y447F, Y275) Rep-Cap plasmid, 5ug2. AAV Helper Plasmid, 5ug3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug Expression vector refers only to B01, if you need other expression vector, please click →AAV Expression Vector list | CRO&CDMO& CXO&CMC& Manufacturing company | Inquiry | ||
| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | ||||
| Shipping Cost: | 169.00 | |||
| Total: | ||||
AAV8 capsid variant (Y733F,Y447F,Y275F) tissue tropism and gene transduction
(serotype-specific AAV infection)
The tissue tropism of AAV8 variant (Y733F, Y447F, Y275F) vector has been validated in in Pancreas, Pancreatic Tumors and retina,with potential applications in tissue-specific gene therapy and cancer therapy.
Virus and titer: AAV1/AAV6/AAV8/AAV-Rh10/AAV-DJ/AAV9-GFP, 1×1012 vg/ml Cells: HEK-293T MOI: MOI=1×104 Determine assay: 36 hours post infection, immunofluorescence microscopy
Other AAV Vector System
