AAV-SIG vector system (AAV-SIG expression system, AAV-SIG packaging plasmid system ) (Amp and Kanamycin) (GeneMedi Owned)

GeneMedi (GM) AAV-SIG Vector system is including: 1) AAV-SIG Rep-Cap plasmid (AAV-SIG-RC plasmid) 2) AAV Helper plasmid 3) AAV expression vectors (overexpression or shRNA).

You can produce AAV-SIG particle in 293T cell line in high titer using GeneMedi's AAV-SIG Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

The tissue tropism of AAV-SIG vector has been validated in endothelium, with potential applications in tissue-specific gene therapy.

GeneMedi offers both Ampicillin (Amp) resistance and Kanamycin (Kan) resistance for the AAV Rep-Cap Plasmids, AAV expression Plasmids and AAV helper Plasmid.

Target products collectionGo to AAV vector system >>



Product Description

Cat.NO Product Name Organization Type Price(In USD)
P-PK25 AAV-SIG Vector System
1. AAV-SIG Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Academic 3379
P-PK25 AAV-SIG Vector System
1. AAV-SIG Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Industry R&D
(excluding
CRO&CDMO&CXO)
P-PK25 AAV-SIG Vector System
1. AAV-SIG Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
 CRO&CDMO&
CXO&CMC&
Manufacturing company
P-PK25-Kan AAV-SIG Vector System(Kan resistance)
1. AAV-SIG Rep-Cap Plasmid(Kan resistance), 10mg
2. AAV Helper Plasmid(Kan resistance), 10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), 10mg
 All
P-RC25 AAV-SIG Rep-Cap Plasmid
Academic 2062
P-RC25 AAV-SIG Rep-Cap Plasmid
Industry R&D
(excluding
CRO&CDMO&CXO)
P-RC25 AAV-SIG Rep-Cap Plasmid
CRO&CDMO&
CXO&CMC&
Manufacturing company
P-RC25-Kan AAV-SIG Rep-Cap Plasmid(Kan resistance)
All
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Vector System.
GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Vector System currently.
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.
Terms of sale:
For Seed (5ug):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party.

For plasmid production&lification (≥10mg):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party.

Citation

Title Publication Date
Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response Signal Transduction and Targeted Therapy 2022/9/1
Sja-miR-71a in Schistosome egg-derived extracellular vesicles suppresses liver fibrosis caused by schistosomiasis via targeting semaphorin 4D Journal of Extracellular Vesicles 2020/7/9
ACSL4 Promotes Microglia-Mediated Neuroinflammation by Regulating Lipid Metabolism and VGLL4 expression Brain, Behavior, and Immunity 2023/2/14
Extracellular fibrinogen-binding protein released by intracellular Staphylococcus aureus suppresses host immunity by targeting TRAF3 Nature Communications 2022/9/19
Extracellular Vesicles Derived From Human Dermal Fibroblast Effectively Ameliorate Skin Photoaging via miRNA-22-5p-GDF11 Axis Chemical Engineering Journal 2022/10/6
Tensile Stress‐Activated and Exosome‐Transferred YAP/TAZ‐Notch Circuit Specifies Type H Endothelial Cell for Segmental Bone Regeneration Advanced Science 2024/1/15
Impeding the combination of astrocytic ASCT2 and NLRP3 by talniflumate alleviates neuroinflammation in experimental models of Parkinson's disease Acta Pharmaceutica Sinica B 2022/8/3
Runx1 protects against the pathological progression of osteoarthritis Bone Research 2021/12/7
Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting ER stress-dependent autophagy via PERK and IRE1 signalings JOURNAL OF PINEAL RESEARCH 2017/5/6
TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain Nature Communications 2018/4/18


Validation data

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Associated products and services


Products & Service Products & Service Information
AAV Packaging service Detail
Promise-ORF™ viral CDNA library Detail
Plasmid DNA Rapid Preparation Service Detail