Bexatamig Biosimilar Bispecific Antibody (CD123 × NKp46) for Research
Cat No.: GMP-Bios-INN-1103
Anti-IL3RA/CD123 therapeutic antibody (Pre-made Bexatamig biosimilar,Bispecific (H-gamma1-VH-G1CH1h_L-kappa)_L-kappa-G1hCH2CH3) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Bexatamig (development code NKp46-1) is a bispecific antibody targeting IL-3 receptor alpha (IL3RA) and NKp46 (NCR1). It is developed by Innate Pharma for acute myeloid leukaemia, myelodysplastic syndromes, precursor B-cell lymphoblastic leukaemia-lymphoma. It is in Phase I/II clinical development.
Order Information
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1103-1mg | 1mg | |
| GMP-Bios-INN-1103-10mg | 10mg | |
| GMP-Bios-INN-1103-100mg | 100mg | |
| GMP-Bios-INN-1103-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Bexatamig biosimilar, Bispecific (H-gamma1-VH-G1CH1h_L-kappa)_L-kappa-G1hCH2CH3, Anti-IL3RA/CD123;NCR1/NKP46/NKp46/LY94/CD335 Antibody: Anti-CD123/IL3RA/Interleukin-3 receptor subunit alpha/IL-3 receptor subunit alpha therapeutic antibody |
| INN Name | Bexatamig |
| Target | IL3RA/CD123;NCR1/NKP46/NKp46/LY94/CD335 |
| Format | Bispecific (H-gamma1-VH-G1CH1h_L-kappa)_L-kappa-G1hCH2CH3 |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1;G1 |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I/II |
| Est. Status | Active |
| 100% SI Structure | 4jzj:HL:AB;6ias:HL/6iap:HL |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2024 |
| Year Recommended | 2024 |
| Companies | Innate Pharma |
| Conditions Approved | na |
| Conditions Active | Acute myeloid leukaemia;Myelodysplastic syndromes;Precursor B-cell lymphoblastic leukaemia-lymphoma |
| Conditions Discontinued | na |
| Production | na |
| Development Tech | na |

