Cabotamig Biosimilar Bispecific Antibody (Cadherin-17 × CD3) for Research
Cat No.: GMP-Bios-INN-1118
Anti-CDH17 therapeutic antibody (Pre-made Cabotamig biosimilar,Bispecific (VH-G1CH1h-G4CH2CH3-scFv)) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Cabotamig (development code ARB202) is a bispecific antibody targeting cadherin 17 (CDH17) and CD3. It is developed by Arbele for gastrointestinal cancers. It is in Phase I clinical development.
Order Information
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1118-1mg | 1mg | |
| GMP-Bios-INN-1118-10mg | 10mg | |
| GMP-Bios-INN-1118-100mg | 100mg | |
| GMP-Bios-INN-1118-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Cabotamig biosimilar, Bispecific (VH-G1CH1h-G4CH2CH3-scFv), Anti-CDH17;CD3E Antibody: Anti-Cadherin-17/CDH17/Intestinal peptide-associated transporter HPT-1/Liver-intestine cadherin (LI-cadherin) therapeutic antibody |
| INN Name | Cabotamig |
| Target | CDH17;CD3E |
| Format | Bispecific (VH-G1CH1h-G4CH2CH3-scFv) |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1/G4;na |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2023 |
| Year Recommended | 2024 |
| Companies | Arbele |
| Conditions Approved | na |
| Conditions Active | Cholangiocarcinoma;Colorectal cancer;Gastric cancer;Gastrointestinal cancer;Liver cancer;Pancreatic cancer;Biliary cancer |
| Conditions Discontinued | na |
| Production | na |
| Development Tech | na |

