Cinrebafusp Biosimilar Fusion Protein (HER2) for Research
Cat No.: GMP-Bios-INN-1134
Anti-ERBB2/CD340/HER2 therapeutic antibody (Pre-made Cinrebafusp biosimilar,Fusion Protein) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Cinrebafusp (development code PRS-343) is a bispecific antibody fusion protein targeting HER2 and 4-1BB (TNFRSF9). It is developed by Pieris Pharmaceuticals with Eli Lilly and Seagen for gastric cancer and other solid tumors. It is in Phase II clinical development.
Order Information
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1134-1mg | 1mg | 3090 |
| GMP-Bios-INN-1134-10mg | 10mg | |
| GMP-Bios-INN-1134-100mg | 100mg | |
| GMP-Bios-INN-1134-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Cinrebafusp biosimilar, Fusion Protein targeting ERBB2/CD340/HER2: Recombinant therapeutic protein targeting HER2/ERBB2/CD340/Receptor tyrosine-protein kinase erbB-2 |
| INN Name | Cinrebafusp |
| Target | ERBB2/CD340/HER2 |
| Format | Fusion Protein |
| Derivation | na |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G4 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Active |
| 100% SI Structure | 6bi0:HL:IM/4hkz:BA/6mh2:BA:DC/5xhg:DC:BA/1n8z:BA/6bi2:HL:IM/1fvc:BA:DC/6bhz:HL:IM/6oge:ED/7mn8:DC/7t97:HL:AB:CD:EF/7t99:HL:AB:CD:EF/4ub0:HL/5xhf:BA:DC/8ti4:HL/8tjf:HL:AB/8pwh:BA/8q6j:BA |
| 99% SI Structure | 1fve:BA:DC/4x4x:AB:CD/5tdn:BA:DC/6bgt:BA/7kbp:CC/7t98:AB:HL |
| 95-98% SI Structure | 5tdn:BA:DC/1fvd:BA:DC/5tdp:BA:DC/4x4y:CD:AB/5tdo:BA:DC/6dn0:CD:AB/3be1:HL/3bdy:HL/6my4:HL:AB/6mxs:HL:AB/6my5:AB:HL/6mxr:AB:HL |
| Year Proposed | 2019 |
| Year Recommended | 2020 |
| Companies | Eli Lilly and Company;Pieris Pharmaceuticals;Seagen |
| Conditions Approved | na |
| Conditions Active | Gastic cancer;Solid tumours |
| Conditions Discontinued | na |
| Production | na |
| Development Tech | na |

