Cizutamig Biosimilar Bispecific Antibody (BCMA × CD3) for Research
Cat No.: GMP-Bios-INN-1136
Anti-TNFRSF17/CD269/BCMA/TNFRSF13A therapeutic antibody (Pre-made Cizutamig biosimilar,Bispecific Mixed Domains (L-kappa-H-gamma1_[VH-G1(CH1-h)]_L-kappa)) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Cizutamig (development codes CN-106/CND-106) is a bispecific antibody targeting B cell maturation antigen (BCMA/TNFRSF17) and CD3. It is developed by EpimAb Biotherapeutics and Candid Therapeutics for cancer and myasthenia gravis. It is in Phase I clinical development.
Order Information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. →
| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1136-1mg | 1mg | |
| GMP-Bios-INN-1136-10mg | 10mg | |
| GMP-Bios-INN-1136-100mg | 100mg | |
| GMP-Bios-INN-1136-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Cizutamig biosimilar, Bispecific Mixed Domains (L-kappa-H-gamma1_[VH-G1(CH1-h)]_L-kappa), Anti-TNFRSF17/CD269/BCMA/TNFRSF13A;CD3E Antibody: Anti-TNFRSF17/BCMA/CD269/Tumor necrosis factor receptor superfamily member 17 therapeutic antibody |
| INN Name | Cizutamig |
| Target | TNFRSF17/CD269/BCMA/TNFRSF13A;CD3E |
| Format | Bispecific Mixed Domains (L-kappa-H-gamma1_[VH-G1(CH1-h)]_L-kappa) |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1;G1 |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2024 |
| Year Recommended | na |
| Companies | EpimAb Biotherapeutics;Candid Therapeutics |
| Conditions Approved | na |
| Conditions Active | Cancer;Myasthenia gravis |
| Conditions Discontinued | na |
| Production | na |
| Development Tech | na |

