Clesitamig Biosimilar Trispecific Antibody (DLL3 × CD3 × 4-1BB) for Research
Cat No.: GMP-Bios-INN-1138
Anti-DLL3 therapeutic antibody (Pre-made Clesitamig biosimilar,Bispecific Mixed Domains ((V-kappa-G4CH1-G1h-H-gamma1_L-kappa)_L-kappa)]_(H-gamma1_L-kappa)); Trispecific through dual targetting Fv2) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Clesitamig (development code RO 7616789) is a bispecific antibody targeting DLL3 and CD3. It is developed by Roche for neuroendocrine tumours, small cell lung cancer. It is in Phase I clinical development.
Order Information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. →
| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1138-1mg | 1mg | |
| GMP-Bios-INN-1138-10mg | 10mg | |
| GMP-Bios-INN-1138-100mg | 100mg | |
| GMP-Bios-INN-1138-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Clesitamig biosimilar, Bispecific Mixed Domains ((V-kappa-G4CH1-G1h-H-gamma1_L-kappa)_L-kappa)]_(H-gamma1_L-kappa)); Trispecific through dual targetting Fv2, Anti-DLL3;CD3&TNFRSF9/CD137/4-1BB Antibody: Anti-DLL3/Delta-like protein 3/Drosophila Delta homolog 3 (Delta3)/SCDO1 therapeutic antibody |
| INN Name | Clesitamig |
| Target | DLL3;CD3&TNFRSF9/CD137/4-1BB |
| Format | Bispecific Mixed Domains ((V-kappa-G4CH1-G1h-H-gamma1_L-kappa)_L-kappa)]_(H-gamma1_L-kappa)); Trispecific through dual targetting Fv2 |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G4;G1 |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Active |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2024 |
| Year Recommended | na |
| Companies | Roche |
| Conditions Approved | na |
| Conditions Active | Neuroendocrine tumours;Small cell lung cancer |
| Conditions Discontinued | na |
| Production | na |
| Development Tech | na |

