Danvilostomig Biosimilar Bispecific Antibody (CTLA-4 × PD-1) for Research
Cat No.: GMP-Bios-INN-1151
Anti-CTLA4/CD152 therapeutic antibody (Pre-made Danvilostomig biosimilar,Bispecific Mixed mAb and scFv) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Danvilostomig (development code SI-B003) is a bispecific antibody targeting CTLA-4 and PD-1. It is developed by Sichuan Baili Pharmaceutical and SystImmune for solid tumors. It is in Phase II clinical development.
Order Information
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1151-1mg | 1mg | |
| GMP-Bios-INN-1151-10mg | 10mg | |
| GMP-Bios-INN-1151-100mg | 100mg | |
| GMP-Bios-INN-1151-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Danvilostomig biosimilar, Bispecific Mixed mAb and scFv, Anti-CTLA4/CD152;PDCD1/CD279/PD1 Antibody: Anti-CTLA-4/CD152/CTLA4/Cytotoxic T-lymphocyte protein 4 therapeutic antibody |
| INN Name | Danvilostomig |
| Target | CTLA4/CD152;PDCD1/CD279/PD1 |
| Format | Bispecific Mixed mAb and scFv |
| Derivation | Human |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1;na |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Discontinued |
| 100% SI Structure | 5tru:HL:hl/5xj3:AB:DE:JK:GH/6jc2:HL/6rp8:HL:hl/7elx:HL;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | 7su0:HL:IM/7su1:HL;None |
| Year Proposed | 2022 |
| Year Recommended | na |
| Companies | Sichuan Baili Pharmaceutical;SystImmune |
| Conditions Approved | na |
| Conditions Active | na |
| Conditions Discontinued | Cervical cancer;Colorectal cancer;Gastric cancer;HER2 negative breast cancer;Nasopharyngeal cancer;Non-small cell lung cancer;Oesophageal cancer;Small cell lung cancer;Solid tumours;Squamous cell cancer;Urogenital cancer |
| Production | na |
| Development Tech | na |

