Enristomig Biosimilar Bispecific Single-Domain Antibody (PD-L1 × 4-1BB) for Research
Cat No.: GMP-Bios-INN-1184
Anti-PDL1/CD274 therapeutic antibody (Pre-made Enristomig biosimilar,Bispecific Single Domains (VH-VH'-G1(h-CH2-CH3) Dimer)) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Enristomig (development code INBRX-105) is a bispecific antibody targeting PD-L1 (CD274) and 4-1BB (TNFRSF9). It is developed by Elpiscience Biopharmaceuticals and Inhibrx. It is in Phase I clinical development.
Order Information
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1184-1mg | 1mg | |
| GMP-Bios-INN-1184-10mg | 10mg | |
| GMP-Bios-INN-1184-100mg | 100mg | |
| GMP-Bios-INN-1184-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Enristomig biosimilar, Bispecific Single Domains (VH-VH'-G1(h-CH2-CH3) Dimer), Anti-PDL1/CD274;TNFRSF9/CD137/4-1BB Antibody: Anti-PD-L1/CD274/Programmed cell death 1 ligand 1/PDCD1 ligand 1 therapeutic antibody |
| INN Name | Enristomig |
| Target | PDL1/CD274;TNFRSF9/CD137/4-1BB |
| Format | Bispecific Single Domains (VH-VH'-G1(h-CH2-CH3) Dimer) |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1;G1 |
| VD LC | na;na |
| Highest_Clin_Trial (Jan '20) | Phase-I |
| Est. Status | Discontinued |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2023 |
| Year Recommended | 2024 |
| Companies | Elpiscience Biopharmaceuticals;Inhibrx |
| Conditions Approved | na |
| Conditions Active | na |
| Conditions Discontinued | Hodgkin's disease;Non-Hodgkin's lymphoma;Solid tumours;Non-small cell lung cancer;Oesophageal cancer;Squamous cell cancer |
| Production | na |
| Development Tech | na |

