Products
Tobemstomig Biosimilar Bispecific Antibody (PD-1 × LAG-3) for Research
Cat No.: GMP-Bios-INN-1421
Anti-PDCD1/CD279/PD1 therapeutic antibody (Pre-made Tobemstomig biosimilar,Bispecific mAb with Domain Crossover) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Tobemstomig (development codes RO7247669/RG-6139) is a humanized bispecific monoclonal antibody targeting PD-1 (PDCD1) and LAG3. It is developed by Roche for Melanoma, Liver cancers, Esophageal squamous cell carcinoma in Phase II development.
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1421-1mg | 1mg | |
| GMP-Bios-INN-1421-10mg | 10mg | |
| GMP-Bios-INN-1421-100mg | 100mg | |
| GMP-Bios-INN-1421-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Tobemstomig biosimilar, Bispecific mAb with Domain Crossover, Anti-PDCD1/CD279/PD1;LAG3/CD223 Antibody: Anti-PD-1/CD279/PDCD1/Programmed cell death protein 1 therapeutic antibody |
| INN Name | Tobemstomig |
| Target | PDCD1/CD279/PD1;LAG3/CD223 |
| Format | Bispecific mAb with Domain Crossover |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1;G1 |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Discontinued |
| 100% SI Structure | None;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2022 |
| Year Recommended | 2023 |
| Companies | Roche |
| Conditions Approved | na |
| Conditions Active | na |
| Conditions Discontinued | Melanoma;Liver cancers;Esophageal squamous cell carcinoma |
| Production | na |
| Development Tech | na |
