Products
Volrustomig Biosimilar Bispecific Antibody (CTLA-4 × PD-1) for Research
Cat No.: GMP-Bios-INN-1464
Anti-CTLA4/CD152 therapeutic antibody (Pre-made Volrustomig biosimilar,Bispecific mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Volrustomig (development code MEDI-5752) is a bispecific monoclonal antibody targeting PD-1 (PDCD1) and CTLA-4. It is developed by AstraZeneca for Solid tumours, Renal cell carcinoma in Phase III development.
Order Information
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| Catalog No. | Package | Price(In USD) |
|---|---|---|
| GMP-Bios-INN-1464-1mg | 1mg | |
| GMP-Bios-INN-1464-10mg | 10mg | |
| GMP-Bios-INN-1464-100mg | 100mg | |
| GMP-Bios-INN-1464-xmg | ≥100mg |
Product Details
| Products Name (INN Index) | Pre-Made Volrustomig biosimilar, Bispecific mAb, Anti-CTLA4/CD152;PDCD1/CD279/PD1 Antibody: Anti-CTLA-4/CD152/CTLA4/Cytotoxic T-lymphocyte protein 4 therapeutic antibody |
| INN Name | Volrustomig |
| Target | CTLA4/CD152;PDCD1/CD279/PD1 |
| Format | Bispecific mAb |
| Derivation | Human |
| Species Reactivity | Human |
| CH1+2+3 Isotype | G1 |
| VD LC | Kappa;Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-III |
| Est. Status | Active |
| 100% SI Structure | 5ggu:HL:AB/5ggv:HL;None |
| 99% SI Structure | None;None |
| 95-98% SI Structure | None;None |
| Year Proposed | 2022 |
| Year Recommended | 2023 |
| Companies | AstraZeneca |
| Conditions Approved | na |
| Conditions Active | Solid tumours;Renal cell carcinoma |
| Conditions Discontinued | na |
| Production | na |
| Development Tech | na |
