Pre-made Datopotamab benchmark antibody ( Whole mAb, anti-TACSTD2 therapeutic antibody, Anti-EGP-1/EGP1/GA733-1/GA7331/GP50/M1S1/TROP2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-134

Pre-Made Datopotamab biosimilar, Whole mAb, Anti-TACSTD2 Antibody: Anti-EGP-1/EGP1/GA733-1/GA7331/GP50/M1S1/TROP2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Datopotamab deruxtecan is an antibody drug conjugate (ADC), composed of an humanised anti-TROP2 monoclonal antibody and MAAA 1181a, a derivative of exatecan, a DNA topoisomerase I inhibitor, being developed by Daiichi Sankyo for the treatment of solid tumours including non-small cell lung cancer and breast cancer .

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Catalog No. Package List Price(In USD) Discount off Discount Price
GMP-Bios-ab-134-1mg 1mg 3090 30% 2163

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Datopotamab biosimilar, Whole mAb, Anti-TACSTD2 Antibody: Anti-EGP-1/EGP1/GA733-1/GA7331/GP50/M1S1/TROP2 therapeutic antibody
INN Name Datopotamab
TargetTACSTD2
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-III
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2019
Year Recommended2020
CompaniesDaiichi Sankyo
Conditions Approvedna
Conditions ActiveBreast cancer;Non-small cell lung cancer
Conditions Discontinuedna
Development Techna