Pre-made Praluzatamab benchmark antibody ( Whole mAb, anti-CD166/ALCAM therapeutic antibody, Anti-MEMD Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-454
Pre-Made Praluzatamab biosimilar, Whole mAb, Anti-CD166/ALCAM Antibody: Anti-MEMD therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Praluzatamab Ravtansine is a probody-drug conjugate (PDC) composed of a recombinant antibody targeting the tumor-associated antigen (TAA) CD166, which is masked by a cleavable masking peptide, and conjugated to the cytotoxic agent maytansinoid DM4, with potential antineoplastic activity.
Order information
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Catalog No. | Package | List Price(In USD) | Discount off | Discount Price |
---|---|---|---|---|
GMP-Bios-ab-454-1mg | 1mg | 3090 | Inquiry | Inquiry |
Size: 1mg | 10mg | 100mg
Description
Products Name (INN Index) | Pre-Made Praluzatamab biosimilar, Whole mAb, Anti-CD166/ALCAM Antibody: Anti-MEMD therapeutic antibody |
INN Name | Praluzatamab |
Target | ALCAM |
Format | Whole mAb |
Derivation | |
Species Reactivity | Human |
CH1 Isotype | IgG1 |
VD LC | Kappa |
Highest_Clin_Trial (Jan '20) | Phase-II |
Est. Status | Active |
100% SI Structure | None |
99% SI Structure | None |
95-98% SI Structure | None |
Year Proposed | 2019 |
Year Recommended | 2020 |
Companies | CytomX Therapeutics;Immunogen |
Conditions Approved | na |
Conditions Active | Solid tumours |
Conditions Discontinued | na |
Development Tech | na |
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