Products
Upifitamab Biosimilar Monoclonal Antibody (SLC34A2) for Research
Pre-Made Upifitamab biosimilar, Whole mAb, Anti-SLC34A2 Antibody: Anti-NAPI-3B/NAPI-IIb/NPTIIb/PULAM therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Order Information
| Catalog No. | Package | List Price(In USD) | Discount off | Discount Price |
|---|---|---|---|---|
| GMP-Bios-ab-602-1mg | 1mg | 3090 |
Size： 1mg | 10mg | 100mg
Product Details
| Products Name (INN Index) | Pre-Made Upifitamab biosimilar, Whole mAb, Anti-SLC34A2 Antibody: Anti-NAPI-3B/NAPI-IIb/NPTIIb/PULAM therapeutic antibody |
| INN Name | Upifitamab |
| Target | SLC34A2 |
| Format | Whole mAb |
| Derivation | |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I/II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2019 |
| Year Recommended | 2020 |
| Companies | Mersana Therapeutics |
| Conditions Approved | na |
| Conditions Active | Non-small cell lung cancer;Ovarian cancer |
| Conditions Discontinued | na |
| Development Tech | na |
About target - SLC34A2
1. Protein Sodium-dependent phosphate transport protein 2B
2. Gene SLC34A2
3. Organism Homo sapiens (Human)
Function
May be involved in actively transporting phosphate into cells via Na+ cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli.
pH dependence
Optimum pH is 6.6.
