Dresbuxelimab Biosimilar Monoclonal Antibody (CD73) for Research

Cat No.: GMP-Bios-ab-660

Pre-Made Dresbuxelimab biosimilar, Whole mAb, Anti-NT5E/CD73 Antibody: Anti-NT/eN/NT5/NTE/eNT/E5NT/CALJA therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Order Information

* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. →
Catalog No. Package Price(In USD)
GMP-Bios-ab-660-1mg 1mg 3090
GMP-Bios-ab-660-10mg 10mg
GMP-Bios-ab-660-100mg 100mg
GMP-Bios-ab-660-xmg ＞100mg



Product Details

Products Name (INN Index) Pre-Made Dresbuxelimab biosimilar, Whole mAb, Anti-NT5E/CD73 Antibody: Anti-NT/eN/NT5/NTE/eNT/E5NT/CALJA therapeutic antibody
INN Name Dresbuxelimab
TargetCD73
FormatWhole  mAb
DerivationHumanized
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-I
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2021
Year Recommendedna
CompaniesAkeso Biopharma
Conditions Approvedna
Conditions ActiveCOVID-19
Conditions Discontinuedna
Development Techna



About target - NT5E

1. Protein 5'-nucleotidase

2. Gene NT5E

3. Organism Homo sapiens (Human)

Function
Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.

Catalytic activity
a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate
EC:3.1.3.5
Source: Rhea.

Cofactor
Zn2+