Products
Pivekimab Biosimilar Monoclonal Antibody (CD123) for Research
Pre-Made Pivekimab biosimilar, Whole mAb, Anti-IL3RA Antibody: Anti-IL3R/CD123/IL3RX/IL3RY/hIL-3Ra therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Order Information
| Catalog No. | Package | List Price(In USD) | Discount off | Discount Price |
|---|---|---|---|---|
| GMP-Bios-ab-686-1mg | 1mg | 3090 |
Size： 1mg | 10mg | 100mg
Product Details
| Products Name (INN Index) | Pre-Made Pivekimab biosimilar, Whole mAb, Anti-IL3RA Antibody: Anti-IL3R/CD123/IL3RX/IL3RY/hIL-3Ra therapeutic antibody |
| INN Name | Pivekimab |
| Target | IL3RA |
| Format | Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-I/II |
| Est. Status | Active |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2021 |
| Year Recommended | na |
| Companies | ImmunoGen |
| Conditions Approved | na |
| Conditions Active | Acute myeloid leukaemia;Blastic plasmacytoid dendritic cell neoplasm |
| Conditions Discontinued | na |
| Development Tech | na |
About target - IL3RA
1. Protein Interleukin-3 receptor subunit alpha
2. Gene IL3RA
3. Organism Homo sapiens (Human)
Function
This is a receptor for interleukin-3.
Miscellaneous
The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.
