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Rat Ctnnb1/Catnb ORF/cDNA clone-Lentivirus plasmid (NM_053357.2)
Pre-made Rat Ctnnb1/Catnb Lentiviral expression plasmid for Ctnnb1 lentivirus packaging, Ctnnb1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
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Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMLV000041 | Rat Ctnnb1 Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMLV000041 |
| Gene Name | Ctnnb1 |
| Accession Number | NM_053357.2 |
| Gene ID | 84353 |
| Species | Rat |
| Product Type | Lentivirus plasmid (overexpression) |
| Insert Length | 2346 bp |
| Gene Alias | Catnb |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocinmyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
| Target ID | GM-T82795 |
| Target Name | CTNNB1 |
| Gene ID | 1499, 12387, 574265, 84353, 101097342, 477032, 539003, 100055241 |
| Gene Symbol and Synonyms | armadillo,Bfc,Catnb,CTNNB,CTNNB1,EVR7,Jup,Mesc,MRD19,NEDSDV |
| Uniprot Accession | P35222 |
| Uniprot Entry Name | CTNB1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | breast cancer |
| Gene Ensembl | ENSG00000168036 |
| Target Classification | Checkpoint-Immuno Oncology, Pathway |
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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