Human LY96/ESOP-1/ly-96 ORF/cDNA clone-Lentivirus particle (NM_015364)

Cat. No.: vGMLP002134

Pre-made Human LY96/ESOP-1/ly-96 Lentiviral expression plasmid for LY96 lentivirus packaging, LY96 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP002134 Human LY96 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP002134
Gene Name LY96
Accession Number NM_015364
Gene ID 23643
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 483 bp
Gene Alias ESOP-1,ly-96,MD-2,MD2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTTACCATTTCTGTTTTTTTCCACCCTGTTTTCTTCCATATTTACTGAAGCTCAGAAGCAGTATTGGGTCTGCAACTCATCCGATGCAAGTATTTCATACACCTACTGTGATAAAATGCAATACCCAATTTCAATTAATGTTAACCCCTGTATAGAATTGAAAAGATCCAAAGGATTATTGCACATTTTCTACATTCCAAGGAGAGATTTAAAGCAATTATATTTCAATCTCTATATAACTGTCAACACCATGAATCTTCCAAAGCGCAAAGAAGTTATTTGCCGAGGATCTGATGACGATTACTCTTTTTGCAGAGCTCTGAAGGGAGAGACTGTGAATACAACAATATCATTCTCCTTCAAGGGAATAAAATTTTCTAAGGGAAAATACAAATGTGTTGTTGAAGCTATTTCTGGGAGCCCAGAAGAAATGCTCTTTTGCTTGGAGTTTGTCATCCTACACCAACCTAATTCAAATTAG
ORF Protein Sequence MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T52382-Ab Anti-LY96/ ESOP-1/ MD-2 monoclonal antibody
    Target Antigen GM-Tg-g-T52382-Ag LY96 VLP (virus-like particle)
    ORF Viral Vector pGMLP002134 Human LY96 Lentivirus plasmid
    ORF Viral Vector vGMLP002134 Human LY96 Lentivirus particle


    Target information

    Target ID GM-T52382
    Target Name LY96
    Gene ID 23643, 17087, 696778, 448830, 101100862, 610524, 613753, 100034040
    Gene Symbol and Synonyms ESOP-1,ly-96,LY96,MD-2,MD2
    Uniprot Accession Q9Y6Y9
    Uniprot Entry Name LY96_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000154589
    Target Classification Not Available

    This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]



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