- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-INGR1/ IFNGR1/ CD119 monoclonal antibody
Anti-INGR1/ IFNGR1/ CD119 antibody for FACS & in-vivo assay
Go to IFNGR1/IFNGR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IO067-Ab-1/ GM-Tg-hg-IO067-Ab-2 | Anti-Human IFNGR1 monoclonal antibody | Human |
| GM-Tg-rg-IO067-Ab-1/ GM-Tg-rg-IO067-Ab-2 | Anti-Rat IFNGR1 monoclonal antibody | Rat |
| GM-Tg-mg-IO067-Ab-1/ GM-Tg-mg-IO067-Ab-2 | Anti-Mouse IFNGR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IO067-Ab-1/ GM-Tg-cynog-IO067-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IFNGR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IO067-Ab-1/ GM-Tg-felg-IO067-Ab-2 | Anti-Feline IFNGR1 monoclonal antibody | Feline |
| GM-Tg-cang-IO067-Ab-1/ GM-Tg-cang-IO067-Ab-2 | Anti-Canine IFNGR1 monoclonal antibody | Canine |
| GM-Tg-bovg-IO067-Ab-1/ GM-Tg-bovg-IO067-Ab-2 | Anti-Bovine IFNGR1 monoclonal antibody | Bovine |
| GM-Tg-equg-IO067-Ab-1/ GM-Tg-equg-IO067-Ab-2 | Anti-Equine IFNGR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IO067-Ab-1/ GM-Tg-hg-IO067-Ab-2; GM-Tg-rg-IO067-Ab-1/ GM-Tg-rg-IO067-Ab-2; GM-Tg-mg-IO067-Ab-1/ GM-Tg-mg-IO067-Ab-2; GM-Tg-cynog-IO067-Ab-1/ GM-Tg-cynog-IO067-Ab-2; GM-Tg-felg-IO067-Ab-1/ GM-Tg-felg-IO067-Ab-2; GM-Tg-cang-IO067-Ab-1/ GM-Tg-cang-IO067-Ab-2; GM-Tg-bovg-IO067-Ab-1/ GM-Tg-bovg-IO067-Ab-2; GM-Tg-equg-IO067-Ab-1/ GM-Tg-equg-IO067-Ab-2 |
| Products Name | Anti-IFNGR1 monoclonal antibody |
| Format | mab |
| Target Name | IFNGR1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IFNGR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species INGR1/ IFNGR1/ CD119 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-IO067-Ag-1 | interferon gamma receptor 1 (IFNGR1) protein |
| ORF Viral Vector | pGMLPm001350 | mouse Ifngr1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001350 | mouse Ifngr1 Lentivirus particle |
Target information
| Target ID | GM-IO067 |
| Target Name | IFNGR1 |
| Gene ID | 3459,15979,116465,100423877,100856077,101086811,508619,100073195 |
| Gene Symbol and Synonyms | CD119,Ifgr,IFN-gammaR,IFNGR,IFNGR1,IFNR1,IMD27A,IMD27B,Nktar |
| Uniprot Accession | P15260 |
| Uniprot Entry Name | INGR1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000027697 |
| Target Classification | N/A |
The target: IFNGR1, gene name: IFNGR1, also named as CD119, IFNGR, IMD27A, IMD27B. This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
