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Anti-SLC33A1 monoclonal antibody
Pre-made anti-SLC33A1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC33A1/SLC33A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0002-Ab-1/ GM-Tg-hg-IP0002-Ab-2 | Anti-Human SLC33A1 monoclonal antibody | Human |
| GM-Tg-rg-IP0002-Ab-1/ GM-Tg-rg-IP0002-Ab-2 | Anti-Rat SLC33A1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0002-Ab-1/ GM-Tg-mg-IP0002-Ab-2 | Anti-Mouse SLC33A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0002-Ab-1/ GM-Tg-cynog-IP0002-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC33A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0002-Ab-1/ GM-Tg-felg-IP0002-Ab-2 | Anti-Feline SLC33A1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0002-Ab-1/ GM-Tg-cang-IP0002-Ab-2 | Anti-Canine SLC33A1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0002-Ab-1/ GM-Tg-bovg-IP0002-Ab-2 | Anti-Bovine SLC33A1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0002-Ab-1/ GM-Tg-equg-IP0002-Ab-2 | Anti-Equine SLC33A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0002-Ab-1/ GM-Tg-hg-IP0002-Ab-2; GM-Tg-rg-IP0002-Ab-1/ GM-Tg-rg-IP0002-Ab-2; GM-Tg-mg-IP0002-Ab-1/ GM-Tg-mg-IP0002-Ab-2; GM-Tg-cynog-IP0002-Ab-1/ GM-Tg-cynog-IP0002-Ab-2; GM-Tg-felg-IP0002-Ab-1/ GM-Tg-felg-IP0002-Ab-2; GM-Tg-cang-IP0002-Ab-1/ GM-Tg-cang-IP0002-Ab-2; GM-Tg-bovg-IP0002-Ab-1/ GM-Tg-bovg-IP0002-Ab-2; GM-Tg-equg-IP0002-Ab-1/ GM-Tg-equg-IP0002-Ab-2 |
| Products Name | Anti-SLC33A1 monoclonal antibody |
| Format | mab |
| Target Name | SLC33A1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC33A1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0002-Ag-1 | Recombinant multi-species ACATN/ SLC33A1/ AT-1 protein |
| ORF Viral Vector | pGMLP004379 | human SLC33A1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004379 | human SLC33A1 Lentivirus particle |
| ORF Viral Vector | pGMLPm005442 | mouse Slc33a1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005442 | mouse Slc33a1 Lentivirus particle |
Target information
| Target ID | GM-IP0002 |
| Target Name | SLC33A1 |
| Gene ID | 9197,11416,64018,721420,485724,101086745,517797,100051998 |
| Gene Symbol and Synonyms | ACATN,AT-1,AT1,CCHLND,D630022N01Rik,SLC33A1,SPG42 |
| Uniprot Accession | O00400,Q6AYY8 |
| Uniprot Entry Name | ACATN_HUMAN,ACATN_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000169359 |
| Target Classification | N/A |
The target: SLC33A1, gene name: SLC33A1, also named as ACATN, AT-1, AT1, CCHLND, SPG42. The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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