Anti-REL1/ RLN1/ H1 functional antibody for cell culture, ELISA & in-vivo assay| GMab

Pre-made anti-RLN1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-RLN1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: RLN1, gene name: RLN1, also named as H1, H1RLX, RLXH1, bA12D24.3.1, bA12D24.3.2. Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-SE1241-Ab-1-1mg	5150	3090
GM-Tg-hg-SE1241-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-SE1241-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-SE1241-Ab-2-1mg	5150	3090
GM-Tg-hg-SE1241-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-SE1241-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-SE1241-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-SE1241-Ab-1, GM-Tg-hg-SE1241-Ab-2
Products Name	Anti-RLN1 monoclonal antibody
Format	mab
Target Name	RLN1
Gene ID	RLN1
Gene Name	RLN1
Gene Alias	H1, H1RLX, RLXH1, bA12D24.3.1, bA12D24.3.2
Protein Sub-location	Secreted Protein/Potential Cytokines
Category of antibody	FACS/Biofunctional Antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Tag	Fc
Products description	Pre-made anti-RLN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.