- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-REL2/ RLN2/ H2 functional antibody
Anti-REL2/ RLN2/ H2 functional antibody for cell culture, ELISA & in-vivo assay
Go to RLN2/RLN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1242-Ab-1/ GM-Tg-hg-SE1242-Ab-2 | Anti-Human RLN2 monoclonal antibody | Human |
| GM-Tg-rg-SE1242-Ab-1/ GM-Tg-rg-SE1242-Ab-2 | Anti-Rat RLN2 monoclonal antibody | Rat |
| GM-Tg-mg-SE1242-Ab-1/ GM-Tg-mg-SE1242-Ab-2 | Anti-Mouse RLN2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1242-Ab-1/ GM-Tg-cynog-SE1242-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RLN2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1242-Ab-1/ GM-Tg-felg-SE1242-Ab-2 | Anti-Feline RLN2 monoclonal antibody | Feline |
| GM-Tg-cang-SE1242-Ab-1/ GM-Tg-cang-SE1242-Ab-2 | Anti-Canine RLN2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1242-Ab-1/ GM-Tg-bovg-SE1242-Ab-2 | Anti-Bovine RLN2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1242-Ab-1/ GM-Tg-equg-SE1242-Ab-2 | Anti-Equine RLN2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1242-Ab-1/ GM-Tg-hg-SE1242-Ab-2; GM-Tg-rg-SE1242-Ab-1/ GM-Tg-rg-SE1242-Ab-2; GM-Tg-mg-SE1242-Ab-1/ GM-Tg-mg-SE1242-Ab-2; GM-Tg-cynog-SE1242-Ab-1/ GM-Tg-cynog-SE1242-Ab-2; GM-Tg-felg-SE1242-Ab-1/ GM-Tg-felg-SE1242-Ab-2; GM-Tg-cang-SE1242-Ab-1/ GM-Tg-cang-SE1242-Ab-2; GM-Tg-bovg-SE1242-Ab-1/ GM-Tg-bovg-SE1242-Ab-2; GM-Tg-equg-SE1242-Ab-1/ GM-Tg-equg-SE1242-Ab-2 |
| Products Name | Anti-RLN2 monoclonal antibody |
| Format | mab |
| Target Name | RLN2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RLN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1242-Ag-1 | Recombinant multi-species REL2/ RLN2/ H2 protein |
Target information
| Target ID | GM-SE1242 |
| Target Name | RLN2 |
| Gene ID | 6019 |
| Gene Symbol and Synonyms | bA12D24.1.1,bA12D24.1.2,H2,H2-RLX,relaxin,RLN,RLN1,RLN2,RLXH2 |
| Uniprot Accession | P04090,Q9TRM8 |
| Uniprot Entry Name | REL2_HUMAN,RELX_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000107014 |
| Target Classification | N/A |
The target: RLN2, gene name: RLN2, also named as H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2. This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
