Anti-SMR3A/ P-B1/ PBI functional antibody

Anti-SMR3A/ P-B1/ PBI functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SMR3A/SMR3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1296-Ab-1/ GM-Tg-hg-SE1296-Ab-2Anti-Human SMR3A monoclonal antibodyHuman
GM-Tg-rg-SE1296-Ab-1/ GM-Tg-rg-SE1296-Ab-2Anti-Rat SMR3A monoclonal antibodyRat
GM-Tg-mg-SE1296-Ab-1/ GM-Tg-mg-SE1296-Ab-2Anti-Mouse SMR3A monoclonal antibodyMouse
GM-Tg-cynog-SE1296-Ab-1/ GM-Tg-cynog-SE1296-Ab-2Anti-Cynomolgus/ Rhesus macaque SMR3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1296-Ab-1/ GM-Tg-felg-SE1296-Ab-2Anti-Feline SMR3A monoclonal antibodyFeline
GM-Tg-cang-SE1296-Ab-1/ GM-Tg-cang-SE1296-Ab-2Anti-Canine SMR3A monoclonal antibodyCanine
GM-Tg-bovg-SE1296-Ab-1/ GM-Tg-bovg-SE1296-Ab-2Anti-Bovine SMR3A monoclonal antibodyBovine
GM-Tg-equg-SE1296-Ab-1/ GM-Tg-equg-SE1296-Ab-2Anti-Equine SMR3A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1296-Ab-1/ GM-Tg-hg-SE1296-Ab-2; GM-Tg-rg-SE1296-Ab-1/ GM-Tg-rg-SE1296-Ab-2;
GM-Tg-mg-SE1296-Ab-1/ GM-Tg-mg-SE1296-Ab-2; GM-Tg-cynog-SE1296-Ab-1/ GM-Tg-cynog-SE1296-Ab-2;
GM-Tg-felg-SE1296-Ab-1/ GM-Tg-felg-SE1296-Ab-2; GM-Tg-cang-SE1296-Ab-1/ GM-Tg-cang-SE1296-Ab-2;
GM-Tg-bovg-SE1296-Ab-1/ GM-Tg-bovg-SE1296-Ab-2; GM-Tg-equg-SE1296-Ab-1/ GM-Tg-equg-SE1296-Ab-2
Products NameAnti-SMR3A monoclonal antibody
Formatmab
Target NameSMR3A
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SMR3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1296-Ag-1Recombinant multi-species SMR3A/ P-B1/ PBI protein


    Target information

    Target IDGM-SE1296
    Target NameSMR3A
    Gene ID26952,707477,102900847
    Gene Symbol and SynonymsP-B1,PBI,PRL5,PROL5,SMR3A
    Uniprot AccessionQ99954
    Uniprot Entry NameSMR3A_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000109208
    Target ClassificationN/A

    The target: SMR3A, gene name: SMR3A, also named as P-B1, PBI, PRL5, PROL5. Predicted to enable endopeptidase inhibitor activity. Predicted to be involved in regulation of sensory perception of pain. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.