Anti-WDR25/ C14orf67 functional antibody

Anti-WDR25/ C14orf67 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WDR25/WDR25 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1371-Ab-1/ GM-Tg-hg-SE1371-Ab-2Anti-Human WDR25 monoclonal antibodyHuman
GM-Tg-rg-SE1371-Ab-1/ GM-Tg-rg-SE1371-Ab-2Anti-Rat WDR25 monoclonal antibodyRat
GM-Tg-mg-SE1371-Ab-1/ GM-Tg-mg-SE1371-Ab-2Anti-Mouse WDR25 monoclonal antibodyMouse
GM-Tg-cynog-SE1371-Ab-1/ GM-Tg-cynog-SE1371-Ab-2Anti-Cynomolgus/ Rhesus macaque WDR25 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1371-Ab-1/ GM-Tg-felg-SE1371-Ab-2Anti-Feline WDR25 monoclonal antibodyFeline
GM-Tg-cang-SE1371-Ab-1/ GM-Tg-cang-SE1371-Ab-2Anti-Canine WDR25 monoclonal antibodyCanine
GM-Tg-bovg-SE1371-Ab-1/ GM-Tg-bovg-SE1371-Ab-2Anti-Bovine WDR25 monoclonal antibodyBovine
GM-Tg-equg-SE1371-Ab-1/ GM-Tg-equg-SE1371-Ab-2Anti-Equine WDR25 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1371-Ab-1/ GM-Tg-hg-SE1371-Ab-2; GM-Tg-rg-SE1371-Ab-1/ GM-Tg-rg-SE1371-Ab-2;
GM-Tg-mg-SE1371-Ab-1/ GM-Tg-mg-SE1371-Ab-2; GM-Tg-cynog-SE1371-Ab-1/ GM-Tg-cynog-SE1371-Ab-2;
GM-Tg-felg-SE1371-Ab-1/ GM-Tg-felg-SE1371-Ab-2; GM-Tg-cang-SE1371-Ab-1/ GM-Tg-cang-SE1371-Ab-2;
GM-Tg-bovg-SE1371-Ab-1/ GM-Tg-bovg-SE1371-Ab-2; GM-Tg-equg-SE1371-Ab-1/ GM-Tg-equg-SE1371-Ab-2
Products NameAnti-WDR25 monoclonal antibody
Formatmab
Target NameWDR25
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WDR25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1371-Ag-1Recombinant multi-species WDR25/ C14orf67 protein


    Target information

    Target IDGM-SE1371
    Target NameWDR25
    Gene ID79446,212198,314443,717667,490858,101081309,527651,100055415
    Gene Symbol and SynonymsB930090D16Rik,C14orf67,RGD1562505,RGD1565864,WDR25,Wdr25l
    Uniprot AccessionQ64LD2
    Uniprot Entry NameWDR25_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000176473
    Target ClassificationN/A

    The target: WDR25, gene name: WDR25, also named as C14orf67. This gene encodes a protein containing 7 WD repeats. WD repeats are approximately 30 to 40-amino acid domains containing several conserved residues, typically having a Tryptophan-Aspartic acid dipeptide (WD) at the C-terminal end. WD domains are involved in protein-protein interactions in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.