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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Cat No.: GM-Tg-hg-SE1500-Ab

Pre-made anti-CABLES1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CABLES1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: CABLES1, gene name: CABLES1, also named as CABL1, CABLES, HsT2563, IK3-1. This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

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Catalog No.List Price (In USD)Discount Price (In USD)Qty (Quantity)Sum (In USD)
GM-Tg-hg-SE1500-Ab-1-1mg51503090
GM-Tg-hg-SE1500-Ab-1-10mgInquiryInquiry
GM-Tg-hg-SE1500-Ab-1-100mgInquiryInquiry
GM-Tg-hg-SE1500-Ab-2-1mg51503090
GM-Tg-hg-SE1500-Ab-2-10mgInquiryInquiry
GM-Tg-hg-SE1500-Ab-2-100mgInquiryInquiry
GM-Tg-hg-SE1500-Ab-xmgInquiryInquiry
Shipping Cost:760.00
Total:



Description

Catalog No.GM-Tg-hg-SE1500-Ab-1, GM-Tg-hg-SE1500-Ab-2
Products Name Anti-CABLES1 monoclonal antibody
Formatmab
Target NameCABLES1
Gene IDCABLES1
Gene NameCABLES1
Gene AliasCABL1, CABLES, HsT2563, IK3-1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
Species ReactivityHuman(H)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CABLES1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.