Anti-CABL1/ CABLES1/ CABLES functional antibody for cell culture, ELISA & in-vivo assay| GMab

Pre-made anti-CABLES1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CABLES1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: CABLES1, gene name: CABLES1, also named as CABL1, CABLES, HsT2563, IK3-1. This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-SE1500-Ab-1-1mg	5150	3090
GM-Tg-hg-SE1500-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-SE1500-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-SE1500-Ab-2-1mg	5150	3090
GM-Tg-hg-SE1500-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-SE1500-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-SE1500-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-SE1500-Ab-1, GM-Tg-hg-SE1500-Ab-2
Products Name	Anti-CABLES1 monoclonal antibody
Format	mab
Target Name	CABLES1
Gene ID	CABLES1
Gene Name	CABLES1
Gene Alias	CABL1, CABLES, HsT2563, IK3-1
Protein Sub-location	Secreted Protein/Potential Cytokines
Category of antibody	FACS/Biofunctional Antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Tag	Fc
Products description	Pre-made anti-CABLES1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.