
Anti-CABL1/ CABLES1/ CABLES functional antibody for cell culture, ELISA & in-vivo assay| GMab
Cat No.: GM-Tg-hg-SE1500-Ab
Pre-made anti-CABLES1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CABLES1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: CABLES1, gene name: CABLES1, also named as CABL1, CABLES, HsT2563, IK3-1. This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Catalog No. | List Price (In USD) | Discount Price (In USD) | Qty (Quantity) | Sum (In USD) |
---|---|---|---|---|
GM-Tg-hg-SE1500-Ab-1-1mg | 5150 | 3090 | ||
GM-Tg-hg-SE1500-Ab-1-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-SE1500-Ab-1-100mg | Inquiry | Inquiry | GM-Tg-hg-SE1500-Ab-2-1mg | 5150 | 3090 |
GM-Tg-hg-SE1500-Ab-2-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-SE1500-Ab-2-100mg | Inquiry | Inquiry | GM-Tg-hg-SE1500-Ab-xmg | Inquiry | Inquiry |
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Catalog No. | GM-Tg-hg-SE1500-Ab-1, GM-Tg-hg-SE1500-Ab-2 |
Products Name | Anti-CABLES1 monoclonal antibody |
Format | mab |
Target Name | CABLES1 |
Gene ID | CABLES1 |
Gene Name | CABLES1 |
Gene Alias | CABL1, CABLES, HsT2563, IK3-1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CABLES1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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