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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Cat No.: GM-Tg-hg-SE1522-Ab

Pre-made anti-MRPL24 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-MRPL24 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: MRPL24, gene name: MRPL24, also named as L24mt, MRP-L18, MRP-L24. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008].

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Catalog No.List Price (In USD)Discount Price (In USD)Qty (Quantity)Sum (In USD)
GM-Tg-hg-SE1522-Ab-1-1mg51503090
GM-Tg-hg-SE1522-Ab-1-10mgInquiryInquiry
GM-Tg-hg-SE1522-Ab-1-100mgInquiryInquiry
GM-Tg-hg-SE1522-Ab-2-1mg51503090
GM-Tg-hg-SE1522-Ab-2-10mgInquiryInquiry
GM-Tg-hg-SE1522-Ab-2-100mgInquiryInquiry
GM-Tg-hg-SE1522-Ab-xmgInquiryInquiry
Shipping Cost:760.00
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Description

Catalog No.GM-Tg-hg-SE1522-Ab-1, GM-Tg-hg-SE1522-Ab-2
Products Name Anti-MRPL24 monoclonal antibody
Formatmab
Target NameMRPL24
Gene IDMRPL24
Gene NameMRPL24
Gene AliasL24mt, MRP-L18, MRP-L24
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
Species ReactivityHuman(H)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MRPL24 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.