Anti-CXCR1/CD181 monoclonal antibody
The Alternative Names of target: CXCR1, CD181,C-X-C chemokine receptor type 1,CXC-R1, CXCR-1,CDw128a, High affinity interleukin-8 receptor A (IL-8R A), IL-8 receptor type 1,C-C,CD128,CD181,CKR-1,IL8R1,IL8RA,CMKAR1,IL8RBA,CDw128a,C-C-CKR-1
                                                                    Pre-made anti-CXCR1/CD181 monoclonal antibody (mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
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Product information
| Catalog No. | Product Name | Species Reactivity | 
|---|---|---|
| GM-Tg-hg-T00884-Ab-1/ GM-Tg-hg-T00884-Ab-2 | Anti-Human CXCR1/CD181 monoclonal antibody | Human | 
| GM-Tg-rg-T00884-Ab-1/ GM-Tg-rg-T00884-Ab-2 | Anti-Rat CXCR1/CD181 monoclonal antibody | Rat | 
| GM-Tg-mg-T00884-Ab-1/ GM-Tg-mg-T00884-Ab-2 | Anti-Mouse CXCR1/CD181 monoclonal antibody | Mouse | 
| GM-Tg-cynog-T00884-Ab-1/ GM-Tg-cynog-T00884-Ab-2 | Anti-Cynomolgus/Rhesus macaque CXCR1/CD181 monoclonal antibody | Cynomolgus/ Rhesus macaque | 
| GM-Tg-felg-T00884-Ab-1/ GM-Tg-felg-T00884-Ab-2 | Anti-Feline CXCR1/CD181 monoclonal antibody | Feline | 
| GM-Tg-cang-T00884-Ab-1/ GM-Tg-cang-T00884-Ab-2 | Anti-Canine CXCR1/CD181 monoclonal antibody | Canine | 
| GM-Tg-bovg-T00884-Ab-1/ GM-Tg-bovg-T00884-Ab-2 | Anti-Bovine CXCR1/CD181 monoclonal antibody | Bovine | 
| GM-Tg-equg-T00884-Ab-1/ GM-Tg-equg-T00884-Ab-2 | Anti-Equine CXCR1/CD181 monoclonal antibody | Equine | 
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. | 
                                                                    GM-Tg-hg-T00884-Ab-1/ GM-Tg-hg-T00884-Ab-2;
                                                                    GM-Tg-rg-T00884-Ab-1/ GM-Tg-rg-T00884-Ab-2;
                                                                     GM-Tg-mg-T00884-Ab-1/ GM-Tg-mg-T00884-Ab-2; GM-Tg-cynog-T00884-Ab-1/ GM-Tg-cynog-T00884-Ab-2; GM-Tg-felg-T00884-Ab-1/ GM-Tg-felg-T00884-Ab-2; GM-Tg-cang-T00884-Ab-1/ GM-Tg-cang-T00884-Ab-2; GM-Tg-bovg-T00884-Ab-1/ GM-Tg-bovg-T00884-Ab-2; GM-Tg-equg-T00884-Ab-1/ GM-Tg-equg-T00884-Ab-2  | 
                                                            
| Products Name | Anti-CXCR1/CD181 monoclonal antibody | 
| Format | mab | 
| Target Name | CXCR1/CD181 | 
| Protein Sub-location | Transmembrane Protein | 
| Category of antibody | Therapeutics Target, Immuno-oncology Target, Cytokine Target | 
| Derivation (species) | Mouse | 
| CH1+2+3 Isotype  (Receptor identification)  | 
                                                                IgG | 
| Type of Light Chain (VD-LC) | N/A | 
| Expression platform | Mammalian Expression | 
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. | 
| Tag | Fc | 
| Products description | Pre-made anti-CXCR1/CD181 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) | 
| Purity | Purity: ≥95% (SDS-PAGE) | 
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. | 
| Formulation & Reconstitution | 
                                                                    Lyophilized from GM's Protein Stability Buffer2
                                                                    (PSB2,Confidential Ingredients) or PBS
                                                                    (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.  | 
                                                            
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. | 
Reference
Data/case study
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About Gmab

                                                                    
GMab, developed by GeneMedi, constitutes an
                                                                        advanced library of recombinant
                                                                        monoclonal antibodies, each meticulously
                                                                        designed to target specific molecular
                                                                        entities. Leveraging the sophisticated
                                                                        capabilities of GM’s Taurus™ and LIBRA™
                                                                        platforms, GMab synthesizes antibodies
                                                                        characterized by high binding affinity,
                                                                        exceptional physicochemical stability, and
                                                                        optimal developability profiles.
Through
                                                                        expression in mammalian cell lines, GMab has
                                                                        been established as a paradigmatic
                                                                        reference antibody. It holds significance in
                                                                        myriad domains of biological drug
                                                                        discovery, encompassing cellular cultivation,
                                                                        innovative assay methodologies,
                                                                        strategic animal model systematization, in-depth
                                                                        pharmacokinetic & pharmacodynamic
                                                                        (PK/PD) modeling, and intricate mechanism of
                                                                        action (MOA) investigations.
                
                
            
        
        
                                            
                                            
        
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