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Anti-CAT monoclonal antibody
Pre-made anti-CAT monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CAT/CAT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T01597-Ab-1/ GM-Tg-hg-T01597-Ab-2 | Anti-Human CAT monoclonal antibody | Human |
| GM-Tg-rg-T01597-Ab-1/ GM-Tg-rg-T01597-Ab-2 | Anti-Rat CAT monoclonal antibody | Rat |
| GM-Tg-mg-T01597-Ab-1/ GM-Tg-mg-T01597-Ab-2 | Anti-Mouse CAT monoclonal antibody | Mouse |
| GM-Tg-cynog-T01597-Ab-1/ GM-Tg-cynog-T01597-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CAT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T01597-Ab-1/ GM-Tg-felg-T01597-Ab-2 | Anti-Feline CAT monoclonal antibody | Feline |
| GM-Tg-cang-T01597-Ab-1/ GM-Tg-cang-T01597-Ab-2 | Anti-Canine CAT monoclonal antibody | Canine |
| GM-Tg-bovg-T01597-Ab-1/ GM-Tg-bovg-T01597-Ab-2 | Anti-Bovine CAT monoclonal antibody | Bovine |
| GM-Tg-equg-T01597-Ab-1/ GM-Tg-equg-T01597-Ab-2 | Anti-Equine CAT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T01597-Ab-1/ GM-Tg-hg-T01597-Ab-2; GM-Tg-rg-T01597-Ab-1/ GM-Tg-rg-T01597-Ab-2; GM-Tg-mg-T01597-Ab-1/ GM-Tg-mg-T01597-Ab-2; GM-Tg-cynog-T01597-Ab-1/ GM-Tg-cynog-T01597-Ab-2; GM-Tg-felg-T01597-Ab-1/ GM-Tg-felg-T01597-Ab-2; GM-Tg-cang-T01597-Ab-1/ GM-Tg-cang-T01597-Ab-2; GM-Tg-bovg-T01597-Ab-1/ GM-Tg-bovg-T01597-Ab-2; GM-Tg-equg-T01597-Ab-1/ GM-Tg-equg-T01597-Ab-2 |
| Products Name | Anti-CAT monoclonal antibody |
| Format | mab |
| Target Name | CAT |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CAT monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T01597-Ag-1 | Recombinant multi-species CATA/ CAT protein |
| ORF Viral Vector | vGMAP000492 | Human CAT Adenovirus particle |
| ORF Viral Vector | pGMAP000492 | Human CAT Adenovirus plasmid |
| ORF Viral Vector | pGMLPm002689 | mouse Cat Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002689 | mouse Cat Lentivirus particle |
Target information
| Target ID | GM-T01597 |
| Target Name | CAT |
| Gene ID | 847,12359,24248,717406,403474,101093891,531682,100060647 |
| Gene Symbol and Synonyms | 2210418N07,Cas-1,Cas1,CAT,Cat01,Catl,Cs-1,CS1 |
| Uniprot Accession | P04040,P04762,O97492,P00432 |
| Uniprot Entry Name | CATA_HUMAN,CATA_RAT,CATA_CANLF,CATA_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Lung Cancer, Diabetic Nephropathy |
| Gene Ensembl | ENSG00000121691 |
| Target Classification | N/A |
The target: CAT, gene name: CAT, also named as . This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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