Anti-LIRB2/ LILRB2/ CD85D antibody for FACS & in-vivo assay| GMab

Pre-made anti-LILRB2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-LILRB2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: LILRB2, gene name: LILRB2, also named as CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-T07931-Ab-1-1mg	5150	3090
GM-Tg-hg-T07931-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-T07931-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-T07931-Ab-2-1mg	5150	3090
GM-Tg-hg-T07931-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-T07931-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-T07931-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-T07931-Ab-1, GM-Tg-hg-T07931-Ab-2
Products Name	Anti-LILRB2 monoclonal antibody
Format	mab
Target Name	LILRB2
Gene ID	LILRB2
Gene Name	LILRB2
Gene Alias	CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10
Protein Sub-location	Transmembrane Protein
Category of antibody	FACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Tag	Fc
Products description	Pre-made anti-LILRB2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.