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Anti-SSR1/ SSTR1/ SRIF-2 monoclonal antibody
Anti-SSR1/ SSTR1/ SRIF-2 antibody for FACS & in-vivo assay
Go to SSTR1/SSTR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T16633-Ab-1/ GM-Tg-hg-T16633-Ab-2 | Anti-Human SSTR1 monoclonal antibody | Human |
| GM-Tg-rg-T16633-Ab-1/ GM-Tg-rg-T16633-Ab-2 | Anti-Rat SSTR1 monoclonal antibody | Rat |
| GM-Tg-mg-T16633-Ab-1/ GM-Tg-mg-T16633-Ab-2 | Anti-Mouse SSTR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T16633-Ab-1/ GM-Tg-cynog-T16633-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SSTR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T16633-Ab-1/ GM-Tg-felg-T16633-Ab-2 | Anti-Feline SSTR1 monoclonal antibody | Feline |
| GM-Tg-cang-T16633-Ab-1/ GM-Tg-cang-T16633-Ab-2 | Anti-Canine SSTR1 monoclonal antibody | Canine |
| GM-Tg-bovg-T16633-Ab-1/ GM-Tg-bovg-T16633-Ab-2 | Anti-Bovine SSTR1 monoclonal antibody | Bovine |
| GM-Tg-equg-T16633-Ab-1/ GM-Tg-equg-T16633-Ab-2 | Anti-Equine SSTR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T16633-Ab-1/ GM-Tg-hg-T16633-Ab-2; GM-Tg-rg-T16633-Ab-1/ GM-Tg-rg-T16633-Ab-2; GM-Tg-mg-T16633-Ab-1/ GM-Tg-mg-T16633-Ab-2; GM-Tg-cynog-T16633-Ab-1/ GM-Tg-cynog-T16633-Ab-2; GM-Tg-felg-T16633-Ab-1/ GM-Tg-felg-T16633-Ab-2; GM-Tg-cang-T16633-Ab-1/ GM-Tg-cang-T16633-Ab-2; GM-Tg-bovg-T16633-Ab-1/ GM-Tg-bovg-T16633-Ab-2; GM-Tg-equg-T16633-Ab-1/ GM-Tg-equg-T16633-Ab-2 |
| Products Name | Anti-SSTR1 monoclonal antibody |
| Format | mab |
| Target Name | SSTR1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SSTR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SSR1/ SSTR1/ SRIF-2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-T16633 |
| Target Name | SSTR1 |
| Gene ID | 6751,20605,25033,698123,403455,101093025,107131319,100060276 |
| Gene Symbol and Synonyms | Gpcrrna,Smstr-1,Smstr1,SRIF-2,SS-1-R,SS1-R,SS1R,SST1,SSTR1 |
| Uniprot Accession | P30872,P28646,Q49LX5 |
| Uniprot Entry Name | SSR1_HUMAN,SSR1_RAT,SSR1_CANLF |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000139874 |
| Target Classification | GPCR, Tumor-associated antigen (TAA) |
The target: SSTR1, gene name: SSTR1, also named as SRIF-2, SS-1-R, SS1-R, SS1R. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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