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Anti-DDX5 monoclonal antibody
Pre-made anti-DDX5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to DDX5/DDX5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T27918-Ab-1/ GM-Tg-hg-T27918-Ab-2 | Anti-Human DDX5 monoclonal antibody | Human |
| GM-Tg-rg-T27918-Ab-1/ GM-Tg-rg-T27918-Ab-2 | Anti-Rat DDX5 monoclonal antibody | Rat |
| GM-Tg-mg-T27918-Ab-1/ GM-Tg-mg-T27918-Ab-2 | Anti-Mouse DDX5 monoclonal antibody | Mouse |
| GM-Tg-cynog-T27918-Ab-1/ GM-Tg-cynog-T27918-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DDX5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T27918-Ab-1/ GM-Tg-felg-T27918-Ab-2 | Anti-Feline DDX5 monoclonal antibody | Feline |
| GM-Tg-cang-T27918-Ab-1/ GM-Tg-cang-T27918-Ab-2 | Anti-Canine DDX5 monoclonal antibody | Canine |
| GM-Tg-bovg-T27918-Ab-1/ GM-Tg-bovg-T27918-Ab-2 | Anti-Bovine DDX5 monoclonal antibody | Bovine |
| GM-Tg-equg-T27918-Ab-1/ GM-Tg-equg-T27918-Ab-2 | Anti-Equine DDX5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T27918-Ab-1/ GM-Tg-hg-T27918-Ab-2; GM-Tg-rg-T27918-Ab-1/ GM-Tg-rg-T27918-Ab-2; GM-Tg-mg-T27918-Ab-1/ GM-Tg-mg-T27918-Ab-2; GM-Tg-cynog-T27918-Ab-1/ GM-Tg-cynog-T27918-Ab-2; GM-Tg-felg-T27918-Ab-1/ GM-Tg-felg-T27918-Ab-2; GM-Tg-cang-T27918-Ab-1/ GM-Tg-cang-T27918-Ab-2; GM-Tg-bovg-T27918-Ab-1/ GM-Tg-bovg-T27918-Ab-2; GM-Tg-equg-T27918-Ab-1/ GM-Tg-equg-T27918-Ab-2 |
| Products Name | Anti-DDX5 monoclonal antibody |
| Format | mab |
| Target Name | DDX5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-DDX5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T27918-Ag-1 | Recombinant multi-species DDX5/ G17P1/ HLR1 protein |
| ORF Viral Vector | pGMLP001934 | human DDX5 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000174 | human DDX5 AAV particle |
| ORF Viral Vector | vGMLP001934 | human DDX5 Lentivirus particle |
| ORF Viral Vector | pGMAAV000174 | human DDX5 AAV plasmid |
| ORF Viral Vector | pGMLPm002678 | mouse Ddx5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002678 | mouse Ddx5 Lentivirus particle |
Target information
| Target ID | GM-T27918 |
| Target Name | DDX5 |
| Gene ID | 1655,13207,287765,677694,480472,101099414,533700,100064168 |
| Gene Symbol and Synonyms | 2600009A06Rik,DDX5,G17P1,HLR1,HUMP68,p68 |
| Uniprot Accession | P17844 |
| Uniprot Entry Name | DDX5_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000108654 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: DDX5, gene name: DDX5, also named as G17P1, HLR1, HUMP68, p68. This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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