Anti-S19A1/ SLC19A1/ CHMD monoclonal antibody

Anti-S19A1/ SLC19A1/ CHMD antibody for FACS & in-vivo assay

Target products collectionGo to SLC19A1/SLC19A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T35465-Ab-1/ GM-Tg-hg-T35465-Ab-2Anti-Human SLC19A1 monoclonal antibodyHuman
GM-Tg-rg-T35465-Ab-1/ GM-Tg-rg-T35465-Ab-2Anti-Rat SLC19A1 monoclonal antibodyRat
GM-Tg-mg-T35465-Ab-1/ GM-Tg-mg-T35465-Ab-2Anti-Mouse SLC19A1 monoclonal antibodyMouse
GM-Tg-cynog-T35465-Ab-1/ GM-Tg-cynog-T35465-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC19A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T35465-Ab-1/ GM-Tg-felg-T35465-Ab-2Anti-Feline SLC19A1 monoclonal antibodyFeline
GM-Tg-cang-T35465-Ab-1/ GM-Tg-cang-T35465-Ab-2Anti-Canine SLC19A1 monoclonal antibodyCanine
GM-Tg-bovg-T35465-Ab-1/ GM-Tg-bovg-T35465-Ab-2Anti-Bovine SLC19A1 monoclonal antibodyBovine
GM-Tg-equg-T35465-Ab-1/ GM-Tg-equg-T35465-Ab-2Anti-Equine SLC19A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T35465-Ab-1/ GM-Tg-hg-T35465-Ab-2; GM-Tg-rg-T35465-Ab-1/ GM-Tg-rg-T35465-Ab-2;
GM-Tg-mg-T35465-Ab-1/ GM-Tg-mg-T35465-Ab-2; GM-Tg-cynog-T35465-Ab-1/ GM-Tg-cynog-T35465-Ab-2;
GM-Tg-felg-T35465-Ab-1/ GM-Tg-felg-T35465-Ab-2; GM-Tg-cang-T35465-Ab-1/ GM-Tg-cang-T35465-Ab-2;
GM-Tg-bovg-T35465-Ab-1/ GM-Tg-bovg-T35465-Ab-2; GM-Tg-equg-T35465-Ab-1/ GM-Tg-equg-T35465-Ab-2
Products NameAnti-SLC19A1 monoclonal antibody
Formatmab
Target NameSLC19A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC19A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S19A1/ SLC19A1/ CHMD VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T35465
    Target NameSLC19A1
    Gene ID6573,20509,29723,721917,491606,101086247,617307,100055625
    Gene Symbol and SynonymsCHMD,FOLT,hRFC,hSLC19A1,IFC-1,IFC1,MEGAF,MTX-1,MTX1,REFC,RFC,RFC-1,RFC1,RFT-1,SLC19A1
    Uniprot AccessionP41440,Q62866
    Uniprot Entry NameS19A1_HUMAN,S19A1_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseCancer
    Gene EnsemblENSG00000173638
    Target ClassificationTumor-associated antigen (TAA)

    The target: SLC19A1, gene name: SLC19A1, also named as CHMD, FOLT, IFC-1, IFC1, REFC, RFC, RFC1. The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.