Anti-PE2R2/ PTGER2/ EP2 monoclonal antibody

Anti-PE2R2/ PTGER2/ EP2 antibody for FACS & in-vivo assay

Target products collectionGo to PTGER2/PTGER2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T38529-Ab-1/ GM-Tg-hg-T38529-Ab-2Anti-Human PTGER2 monoclonal antibodyHuman
GM-Tg-rg-T38529-Ab-1/ GM-Tg-rg-T38529-Ab-2Anti-Rat PTGER2 monoclonal antibodyRat
GM-Tg-mg-T38529-Ab-1/ GM-Tg-mg-T38529-Ab-2Anti-Mouse PTGER2 monoclonal antibodyMouse
GM-Tg-cynog-T38529-Ab-1/ GM-Tg-cynog-T38529-Ab-2Anti-Cynomolgus/ Rhesus macaque PTGER2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T38529-Ab-1/ GM-Tg-felg-T38529-Ab-2Anti-Feline PTGER2 monoclonal antibodyFeline
GM-Tg-cang-T38529-Ab-1/ GM-Tg-cang-T38529-Ab-2Anti-Canine PTGER2 monoclonal antibodyCanine
GM-Tg-bovg-T38529-Ab-1/ GM-Tg-bovg-T38529-Ab-2Anti-Bovine PTGER2 monoclonal antibodyBovine
GM-Tg-equg-T38529-Ab-1/ GM-Tg-equg-T38529-Ab-2Anti-Equine PTGER2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T38529-Ab-1/ GM-Tg-hg-T38529-Ab-2; GM-Tg-rg-T38529-Ab-1/ GM-Tg-rg-T38529-Ab-2;
GM-Tg-mg-T38529-Ab-1/ GM-Tg-mg-T38529-Ab-2; GM-Tg-cynog-T38529-Ab-1/ GM-Tg-cynog-T38529-Ab-2;
GM-Tg-felg-T38529-Ab-1/ GM-Tg-felg-T38529-Ab-2; GM-Tg-cang-T38529-Ab-1/ GM-Tg-cang-T38529-Ab-2;
GM-Tg-bovg-T38529-Ab-1/ GM-Tg-bovg-T38529-Ab-2; GM-Tg-equg-T38529-Ab-1/ GM-Tg-equg-T38529-Ab-2
Products NameAnti-PTGER2 monoclonal antibody
Formatmab
Target NamePTGER2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PTGER2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PE2R2/ PTGER2/ EP2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003585human PTGER2 Lentivirus plasmid
    ORF Viral VectorvGMLP003585human PTGER2 Lentivirus particle
    ORF Viral VectorpGMLPm002784mouse Ptger2 Lentivirus plasmid
    ORF Viral VectorvGMLPm002784mouse Ptger2 Lentivirus particle


    Target information

    Target IDGM-T38529
    Target NamePTGER2
    Gene ID5732,19217,81752,708024,403797,100169967,282329,100067279
    Gene Symbol and SynonymsEP2,Ptger-ep2,PTGER2,Ptgerep2
    Uniprot AccessionP43116,Q62928,Q9XT82
    Uniprot Entry NamePE2R2_HUMAN,PE2R2_RAT,PE2R2_CANLF
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target
    DiseaseCancer
    Gene EnsemblENSG00000125384
    Target ClassificationCheckpoint-Immuno Oncology, GPCR, Tumor-associated antigen (TAA)

    The target: PTGER2, gene name: PTGER2, also named as EP2. This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.