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Anti-ADA1D/ ADRA1D/ ADRA1 monoclonal antibody
Anti-ADA1D/ ADRA1D/ ADRA1 antibody for FACS & in-vivo assay
Go to ADRA1D/ADRA1D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T53381-Ab-1/ GM-Tg-hg-T53381-Ab-2 | Anti-Human ADRA1D monoclonal antibody | Human |
| GM-Tg-rg-T53381-Ab-1/ GM-Tg-rg-T53381-Ab-2 | Anti-Rat ADRA1D monoclonal antibody | Rat |
| GM-Tg-mg-T53381-Ab-1/ GM-Tg-mg-T53381-Ab-2 | Anti-Mouse ADRA1D monoclonal antibody | Mouse |
| GM-Tg-cynog-T53381-Ab-1/ GM-Tg-cynog-T53381-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ADRA1D monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T53381-Ab-1/ GM-Tg-felg-T53381-Ab-2 | Anti-Feline ADRA1D monoclonal antibody | Feline |
| GM-Tg-cang-T53381-Ab-1/ GM-Tg-cang-T53381-Ab-2 | Anti-Canine ADRA1D monoclonal antibody | Canine |
| GM-Tg-bovg-T53381-Ab-1/ GM-Tg-bovg-T53381-Ab-2 | Anti-Bovine ADRA1D monoclonal antibody | Bovine |
| GM-Tg-equg-T53381-Ab-1/ GM-Tg-equg-T53381-Ab-2 | Anti-Equine ADRA1D monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T53381-Ab-1/ GM-Tg-hg-T53381-Ab-2; GM-Tg-rg-T53381-Ab-1/ GM-Tg-rg-T53381-Ab-2; GM-Tg-mg-T53381-Ab-1/ GM-Tg-mg-T53381-Ab-2; GM-Tg-cynog-T53381-Ab-1/ GM-Tg-cynog-T53381-Ab-2; GM-Tg-felg-T53381-Ab-1/ GM-Tg-felg-T53381-Ab-2; GM-Tg-cang-T53381-Ab-1/ GM-Tg-cang-T53381-Ab-2; GM-Tg-bovg-T53381-Ab-1/ GM-Tg-bovg-T53381-Ab-2; GM-Tg-equg-T53381-Ab-1/ GM-Tg-equg-T53381-Ab-2 |
| Products Name | Anti-ADRA1D monoclonal antibody |
| Format | mab |
| Target Name | ADRA1D |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ADRA1D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ADA1D/ ADRA1D/ ADRA1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm005322 | mouse Adra1d Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005322 | mouse Adra1d Lentivirus particle |
Target information
| Target ID | GM-T53381 |
| Target Name | ADRA1D |
| Gene ID | 146,11550,29413,100430996,111092035,101092019,539543,100066003 |
| Gene Symbol and Synonyms | Adra-1,ADRA1,ADRA1A,ADRA1D,ADRA1R,Adrd1,ALPHA1,alpha1D-AR,DAR,dJ779E11.2,Gpcr8,Spr8,[a]1d |
| Uniprot Accession | P25100,P23944 |
| Uniprot Entry Name | ADA1D_HUMAN,ADA1D_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000171873 |
| Target Classification | GPCR |
The target: ADRA1D, gene name: ADRA1D, also named as ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2. Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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