Anti-OPRD/ OPRD1/ DOP monoclonal antibody

Anti-OPRD/ OPRD1/ DOP antibody for FACS & in-vivo assay

Target products collectionGo to OPRD1/OPRD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T58992-Ab-1/ GM-Tg-hg-T58992-Ab-2Anti-Human OPRD1 monoclonal antibodyHuman
GM-Tg-rg-T58992-Ab-1/ GM-Tg-rg-T58992-Ab-2Anti-Rat OPRD1 monoclonal antibodyRat
GM-Tg-mg-T58992-Ab-1/ GM-Tg-mg-T58992-Ab-2Anti-Mouse OPRD1 monoclonal antibodyMouse
GM-Tg-cynog-T58992-Ab-1/ GM-Tg-cynog-T58992-Ab-2Anti-Cynomolgus/ Rhesus macaque OPRD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T58992-Ab-1/ GM-Tg-felg-T58992-Ab-2Anti-Feline OPRD1 monoclonal antibodyFeline
GM-Tg-cang-T58992-Ab-1/ GM-Tg-cang-T58992-Ab-2Anti-Canine OPRD1 monoclonal antibodyCanine
GM-Tg-bovg-T58992-Ab-1/ GM-Tg-bovg-T58992-Ab-2Anti-Bovine OPRD1 monoclonal antibodyBovine
GM-Tg-equg-T58992-Ab-1/ GM-Tg-equg-T58992-Ab-2Anti-Equine OPRD1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T58992-Ab-1/ GM-Tg-hg-T58992-Ab-2; GM-Tg-rg-T58992-Ab-1/ GM-Tg-rg-T58992-Ab-2;
GM-Tg-mg-T58992-Ab-1/ GM-Tg-mg-T58992-Ab-2; GM-Tg-cynog-T58992-Ab-1/ GM-Tg-cynog-T58992-Ab-2;
GM-Tg-felg-T58992-Ab-1/ GM-Tg-felg-T58992-Ab-2; GM-Tg-cang-T58992-Ab-1/ GM-Tg-cang-T58992-Ab-2;
GM-Tg-bovg-T58992-Ab-1/ GM-Tg-bovg-T58992-Ab-2; GM-Tg-equg-T58992-Ab-1/ GM-Tg-equg-T58992-Ab-2
Products NameAnti-OPRD1 monoclonal antibody
Formatmab
Target NameOPRD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OPRD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OPRD/ OPRD1/ DOP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP002987human OPRD1 Lentivirus particle
    ORF Viral VectorpGMLP002987human OPRD1 Lentivirus plasmid


    Target information

    Target IDGM-T58992
    Target NameOPRD1
    Gene ID4985,18386,24613,717256,487329,101088861,781956,100070646
    Gene Symbol and SynonymsDOP,DOR,DOR-1,DOR1,mDOR,Nbor,OPRD,OPRD1
    Uniprot AccessionP41143,P33533
    Uniprot Entry NameOPRD_HUMAN,OPRD_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000116329
    Target ClassificationGPCR

    The target: OPRD1, gene name: OPRD1, also named as DOP, DOR, DOR1, OPRD. Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled opioid receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Is intrinsic component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.