Anti-PF2R/ PTGFR/ FP monoclonal antibody

Anti-PF2R/ PTGFR/ FP antibody for FACS & in-vivo assay

Target products collectionGo to PTGFR/PTGFR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T75797-Ab-1/ GM-Tg-hg-T75797-Ab-2Anti-Human PTGFR monoclonal antibodyHuman
GM-Tg-rg-T75797-Ab-1/ GM-Tg-rg-T75797-Ab-2Anti-Rat PTGFR monoclonal antibodyRat
GM-Tg-mg-T75797-Ab-1/ GM-Tg-mg-T75797-Ab-2Anti-Mouse PTGFR monoclonal antibodyMouse
GM-Tg-cynog-T75797-Ab-1/ GM-Tg-cynog-T75797-Ab-2Anti-Cynomolgus/ Rhesus macaque PTGFR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T75797-Ab-1/ GM-Tg-felg-T75797-Ab-2Anti-Feline PTGFR monoclonal antibodyFeline
GM-Tg-cang-T75797-Ab-1/ GM-Tg-cang-T75797-Ab-2Anti-Canine PTGFR monoclonal antibodyCanine
GM-Tg-bovg-T75797-Ab-1/ GM-Tg-bovg-T75797-Ab-2Anti-Bovine PTGFR monoclonal antibodyBovine
GM-Tg-equg-T75797-Ab-1/ GM-Tg-equg-T75797-Ab-2Anti-Equine PTGFR monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T75797-Ab-1/ GM-Tg-hg-T75797-Ab-2; GM-Tg-rg-T75797-Ab-1/ GM-Tg-rg-T75797-Ab-2;
GM-Tg-mg-T75797-Ab-1/ GM-Tg-mg-T75797-Ab-2; GM-Tg-cynog-T75797-Ab-1/ GM-Tg-cynog-T75797-Ab-2;
GM-Tg-felg-T75797-Ab-1/ GM-Tg-felg-T75797-Ab-2; GM-Tg-cang-T75797-Ab-1/ GM-Tg-cang-T75797-Ab-2;
GM-Tg-bovg-T75797-Ab-1/ GM-Tg-bovg-T75797-Ab-2; GM-Tg-equg-T75797-Ab-1/ GM-Tg-equg-T75797-Ab-2
Products NameAnti-PTGFR monoclonal antibody
Formatmab
Target NamePTGFR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PTGFR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PF2R/ PTGFR/ FP VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T75797
    Target NamePTGFR
    Gene ID5737,19220,25652,707535,479981,493933,282020,100009714
    Gene Symbol and SynonymsFP,PF2AR,PGF,PTGFR
    Uniprot AccessionP43088,P43118,P37289
    Uniprot Entry NamePF2R_HUMAN,PF2R_RAT,PF2R_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000122420
    Target ClassificationGPCR

    The target: PTGFR, gene name: PTGFR, also named as FP. The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.