Anti-V1AR/ AVPR1A/ AVPR V1a monoclonal antibody

Anti-V1AR/ AVPR1A/ AVPR V1a antibody for FACS & in-vivo assay

Target products collectionGo to V1AR/AVPR1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T79232-Ab-1/ GM-Tg-hg-T79232-Ab-2Anti-Human V1AR/AVPR1A monoclonal antibodyHuman
GM-Tg-rg-T79232-Ab-1/ GM-Tg-rg-T79232-Ab-2Anti-Rat V1AR/AVPR1A monoclonal antibodyRat
GM-Tg-mg-T79232-Ab-1/ GM-Tg-mg-T79232-Ab-2Anti-Mouse V1AR/AVPR1A monoclonal antibodyMouse
GM-Tg-cynog-T79232-Ab-1/ GM-Tg-cynog-T79232-Ab-2Anti-Cynomolgus/ Rhesus macaque V1AR/AVPR1A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T79232-Ab-1/ GM-Tg-felg-T79232-Ab-2Anti-Feline V1AR/AVPR1A monoclonal antibodyFeline
GM-Tg-cang-T79232-Ab-1/ GM-Tg-cang-T79232-Ab-2Anti-Canine V1AR/AVPR1A monoclonal antibodyCanine
GM-Tg-bovg-T79232-Ab-1/ GM-Tg-bovg-T79232-Ab-2Anti-Bovine V1AR/AVPR1A monoclonal antibodyBovine
GM-Tg-equg-T79232-Ab-1/ GM-Tg-equg-T79232-Ab-2Anti-Equine V1AR/AVPR1A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T79232-Ab-1/ GM-Tg-hg-T79232-Ab-2; GM-Tg-rg-T79232-Ab-1/ GM-Tg-rg-T79232-Ab-2;
GM-Tg-mg-T79232-Ab-1/ GM-Tg-mg-T79232-Ab-2; GM-Tg-cynog-T79232-Ab-1/ GM-Tg-cynog-T79232-Ab-2;
GM-Tg-felg-T79232-Ab-1/ GM-Tg-felg-T79232-Ab-2; GM-Tg-cang-T79232-Ab-1/ GM-Tg-cang-T79232-Ab-2;
GM-Tg-bovg-T79232-Ab-1/ GM-Tg-bovg-T79232-Ab-2; GM-Tg-equg-T79232-Ab-1/ GM-Tg-equg-T79232-Ab-2
Products NameAnti-V1AR/AVPR1A monoclonal antibody
Formatmab
Target NameV1AR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-V1AR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species V1AR/ AVPR1A/ AVPR V1a VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T79232
    Target NameV1AR
    Gene ID552,54140,25107,717041,481142,101100229,538439,100056176
    Gene Symbol and SynonymsAVPR,AVPR V1a,AVPR1,AVPR1A,V1a,V1aR
    Uniprot AccessionP37288,P30560
    Uniprot Entry NameV1AR_HUMAN,V1AR_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000166148
    Target ClassificationN/A

    The target: V1AR, gene name: AVPR1A, also named as AVPR V1a, AVPR1, V1aR. The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.