Anti-TRPA1/ ANK™1/ FEPS monoclonal antibody

Anti-TRPA1/ ANK™1/ FEPS antibody for FACS & in-vivo assay

Target products collectionGo to TRPA1/TRPA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T84040-Ab-1/ GM-Tg-hg-T84040-Ab-2Anti-Human TRPA1 monoclonal antibodyHuman
GM-Tg-rg-T84040-Ab-1/ GM-Tg-rg-T84040-Ab-2Anti-Rat TRPA1 monoclonal antibodyRat
GM-Tg-mg-T84040-Ab-1/ GM-Tg-mg-T84040-Ab-2Anti-Mouse TRPA1 monoclonal antibodyMouse
GM-Tg-cynog-T84040-Ab-1/ GM-Tg-cynog-T84040-Ab-2Anti-Cynomolgus/ Rhesus macaque TRPA1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T84040-Ab-1/ GM-Tg-felg-T84040-Ab-2Anti-Feline TRPA1 monoclonal antibodyFeline
GM-Tg-cang-T84040-Ab-1/ GM-Tg-cang-T84040-Ab-2Anti-Canine TRPA1 monoclonal antibodyCanine
GM-Tg-bovg-T84040-Ab-1/ GM-Tg-bovg-T84040-Ab-2Anti-Bovine TRPA1 monoclonal antibodyBovine
GM-Tg-equg-T84040-Ab-1/ GM-Tg-equg-T84040-Ab-2Anti-Equine TRPA1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T84040-Ab-1/ GM-Tg-hg-T84040-Ab-2; GM-Tg-rg-T84040-Ab-1/ GM-Tg-rg-T84040-Ab-2;
GM-Tg-mg-T84040-Ab-1/ GM-Tg-mg-T84040-Ab-2; GM-Tg-cynog-T84040-Ab-1/ GM-Tg-cynog-T84040-Ab-2;
GM-Tg-felg-T84040-Ab-1/ GM-Tg-felg-T84040-Ab-2; GM-Tg-cang-T84040-Ab-1/ GM-Tg-cang-T84040-Ab-2;
GM-Tg-bovg-T84040-Ab-1/ GM-Tg-bovg-T84040-Ab-2; GM-Tg-equg-T84040-Ab-1/ GM-Tg-equg-T84040-Ab-2
Products NameAnti-TRPA1 monoclonal antibody
Formatmab
Target NameTRPA1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TRPA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TRPA1/ ANK™1/ FEPS VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T84040
    Target NameTRPA1
    Gene ID8989,277328,312896,694623,486994,101080611,505317,100061564
    Gene Symbol and SynonymsANK™1,FEPS,FEPS1,p120,TRPA1,TRPA1b
    Uniprot AccessionO75762,Q6RI86
    Uniprot Entry NameTRPA1_HUMAN,TRPA1_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000104321
    Target ClassificationIon Channel

    The target: TRPA1, gene name: TRPA1, also named as ANK™1, FEPS, FEPS1. The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins.  The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.