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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Cat No.: GM-Tg-hg-T86057-Ab

Pre-made anti-URAT1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-URAT1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: URAT1, gene name: SLC22A12, also named as OAT4L, RST, URAT1. The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].

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Catalog No.List Price (In USD)Discount Price (In USD)Qty (Quantity)Sum (In USD)
GM-Tg-hg-T86057-Ab-1-1mg51503090
GM-Tg-hg-T86057-Ab-1-10mgInquiryInquiry
GM-Tg-hg-T86057-Ab-1-100mgInquiryInquiry
GM-Tg-hg-T86057-Ab-2-1mg51503090
GM-Tg-hg-T86057-Ab-2-10mgInquiryInquiry
GM-Tg-hg-T86057-Ab-2-100mgInquiryInquiry
GM-Tg-hg-T86057-Ab-xmgInquiryInquiry
Shipping Cost:760.00
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Description

Catalog No.GM-Tg-hg-T86057-Ab-1, GM-Tg-hg-T86057-Ab-2
Products Name Anti-URAT1/SLC22A12 monoclonal antibody
Formatmab
Target NameURAT1
Gene IDSLC22A12
Gene NameSLC22A12
Gene AliasOAT4L, RST, URAT1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
Species ReactivityHuman(H)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-URAT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.