
Anti-S22AC/ URAT1/ SLC22A12 antibody for FACS & in-vivo assay| GMab
Cat No.: GM-Tg-hg-T86057-Ab
Pre-made anti-URAT1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-URAT1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: URAT1, gene name: SLC22A12, also named as OAT4L, RST, URAT1. The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
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Catalog No. | List Price (In USD) | Discount Price (In USD) | Qty (Quantity) | Sum (In USD) |
---|---|---|---|---|
GM-Tg-hg-T86057-Ab-1-1mg | 5150 | 3090 | ||
GM-Tg-hg-T86057-Ab-1-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T86057-Ab-1-100mg | Inquiry | Inquiry | GM-Tg-hg-T86057-Ab-2-1mg | 5150 | 3090 |
GM-Tg-hg-T86057-Ab-2-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T86057-Ab-2-100mg | Inquiry | Inquiry | GM-Tg-hg-T86057-Ab-xmg | Inquiry | Inquiry |
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Catalog No. | GM-Tg-hg-T86057-Ab-1, GM-Tg-hg-T86057-Ab-2 |
Products Name | Anti-URAT1/SLC22A12 monoclonal antibody |
Format | mab |
Target Name | URAT1 |
Gene ID | SLC22A12 |
Gene Name | SLC22A12 |
Gene Alias | OAT4L, RST, URAT1 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-URAT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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