Anti-SL9A3/ SLC9A3/ DIAR8 monoclonal antibody

Anti-SL9A3/ SLC9A3/ DIAR8 antibody for FACS & in-vivo assay

Target products collectionGo to SLC9A3/SLC9A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T92403-Ab-1/ GM-Tg-hg-T92403-Ab-2Anti-Human SLC9A3 monoclonal antibodyHuman
GM-Tg-rg-T92403-Ab-1/ GM-Tg-rg-T92403-Ab-2Anti-Rat SLC9A3 monoclonal antibodyRat
GM-Tg-mg-T92403-Ab-1/ GM-Tg-mg-T92403-Ab-2Anti-Mouse SLC9A3 monoclonal antibodyMouse
GM-Tg-cynog-T92403-Ab-1/ GM-Tg-cynog-T92403-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC9A3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T92403-Ab-1/ GM-Tg-felg-T92403-Ab-2Anti-Feline SLC9A3 monoclonal antibodyFeline
GM-Tg-cang-T92403-Ab-1/ GM-Tg-cang-T92403-Ab-2Anti-Canine SLC9A3 monoclonal antibodyCanine
GM-Tg-bovg-T92403-Ab-1/ GM-Tg-bovg-T92403-Ab-2Anti-Bovine SLC9A3 monoclonal antibodyBovine
GM-Tg-equg-T92403-Ab-1/ GM-Tg-equg-T92403-Ab-2Anti-Equine SLC9A3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T92403-Ab-1/ GM-Tg-hg-T92403-Ab-2; GM-Tg-rg-T92403-Ab-1/ GM-Tg-rg-T92403-Ab-2;
GM-Tg-mg-T92403-Ab-1/ GM-Tg-mg-T92403-Ab-2; GM-Tg-cynog-T92403-Ab-1/ GM-Tg-cynog-T92403-Ab-2;
GM-Tg-felg-T92403-Ab-1/ GM-Tg-felg-T92403-Ab-2; GM-Tg-cang-T92403-Ab-1/ GM-Tg-cang-T92403-Ab-2;
GM-Tg-bovg-T92403-Ab-1/ GM-Tg-bovg-T92403-Ab-2; GM-Tg-equg-T92403-Ab-1/ GM-Tg-equg-T92403-Ab-2
Products NameAnti-SLC9A3 monoclonal antibody
Formatmab
Target NameSLC9A3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC9A3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SL9A3/ SLC9A3/ DIAR8 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T92403
    Target NameSLC9A3
    Gene ID6550,105243,24784,708641,488073,101082470,407112,100034109
    Gene Symbol and Synonyms9030624O13Rik,DIAR8,NHE-3,NHE3,SLC9A3
    Uniprot AccessionP48764,P26433
    Uniprot Entry NameSL9A3_HUMAN,SL9A3_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000066230
    Target ClassificationN/A

    The target: SLC9A3, gene name: SLC9A3, also named as DIAR8, NHE-3, NHE3. The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22. [provided by RefSeq, Mar 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.