Anti-TAAR1/ TA1/ TAR1 monoclonal antibody

Anti-TAAR1/ TA1/ TAR1 antibody for FACS & in-vivo assay

Target products collectionGo to TAAR1/TAAR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T99524-Ab-1/ GM-Tg-hg-T99524-Ab-2Anti-Human TAAR1 monoclonal antibodyHuman
GM-Tg-rg-T99524-Ab-1/ GM-Tg-rg-T99524-Ab-2Anti-Rat TAAR1 monoclonal antibodyRat
GM-Tg-mg-T99524-Ab-1/ GM-Tg-mg-T99524-Ab-2Anti-Mouse TAAR1 monoclonal antibodyMouse
GM-Tg-cynog-T99524-Ab-1/ GM-Tg-cynog-T99524-Ab-2Anti-Cynomolgus/ Rhesus macaque TAAR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T99524-Ab-1/ GM-Tg-felg-T99524-Ab-2Anti-Feline TAAR1 monoclonal antibodyFeline
GM-Tg-cang-T99524-Ab-1/ GM-Tg-cang-T99524-Ab-2Anti-Canine TAAR1 monoclonal antibodyCanine
GM-Tg-bovg-T99524-Ab-1/ GM-Tg-bovg-T99524-Ab-2Anti-Bovine TAAR1 monoclonal antibodyBovine
GM-Tg-equg-T99524-Ab-1/ GM-Tg-equg-T99524-Ab-2Anti-Equine TAAR1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T99524-Ab-1/ GM-Tg-hg-T99524-Ab-2; GM-Tg-rg-T99524-Ab-1/ GM-Tg-rg-T99524-Ab-2;
GM-Tg-mg-T99524-Ab-1/ GM-Tg-mg-T99524-Ab-2; GM-Tg-cynog-T99524-Ab-1/ GM-Tg-cynog-T99524-Ab-2;
GM-Tg-felg-T99524-Ab-1/ GM-Tg-felg-T99524-Ab-2; GM-Tg-cang-T99524-Ab-1/ GM-Tg-cang-T99524-Ab-2;
GM-Tg-bovg-T99524-Ab-1/ GM-Tg-bovg-T99524-Ab-2; GM-Tg-equg-T99524-Ab-1/ GM-Tg-equg-T99524-Ab-2
Products NameAnti-TAAR1 monoclonal antibody
Formatmab
Target NameTAAR1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TAAR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TAAR1/ TA1/ TAR1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP001582human TAAR1 Lentivirus particle
    ORF Viral VectorpGMLP001582human TAAR1 Lentivirus plasmid
    ORF Viral VectorpGMLPm004009mouse Taar1 Lentivirus plasmid
    ORF Viral VectorvGMLPm004009mouse Taar1 Lentivirus particle


    Target information

    Target IDGM-T99524
    Target NameTAAR1
    Gene ID134864,111174,113914,708944,101096731,104969593,106780887
    Gene Symbol and SynonymsTA1,TAAR1,taR-1,TAR1,TRAR1
    Uniprot AccessionQ96RJ0,Q923Y9,Q8HZ64
    Uniprot Entry NameTAAR1_HUMAN,TAAR1_MACMU,TAAR1_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000146399
    Target ClassificationGPCR

    The target: TAAR1, gene name: TAAR1, also named as TA1, TAR1, TRAR1. The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopamine, and tryptamine. While primarily functioning in neurologic systems, there is evidence that this gene is involved in blood cell and immunologic functions as well. This gene is thought to be intronless. [provided by RefSeq, Nov 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.