Anti-PI2R/ PTGIR/ IP monoclonal antibody

Anti-PI2R/ PTGIR/ IP antibody for FACS & in-vivo assay

Target products collectionGo to PTGIR/PTGIR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T99954-Ab-1/ GM-Tg-hg-T99954-Ab-2Anti-Human PTGIR monoclonal antibodyHuman
GM-Tg-rg-T99954-Ab-1/ GM-Tg-rg-T99954-Ab-2Anti-Rat PTGIR monoclonal antibodyRat
GM-Tg-mg-T99954-Ab-1/ GM-Tg-mg-T99954-Ab-2Anti-Mouse PTGIR monoclonal antibodyMouse
GM-Tg-cynog-T99954-Ab-1/ GM-Tg-cynog-T99954-Ab-2Anti-Cynomolgus/ Rhesus macaque PTGIR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T99954-Ab-1/ GM-Tg-felg-T99954-Ab-2Anti-Feline PTGIR monoclonal antibodyFeline
GM-Tg-cang-T99954-Ab-1/ GM-Tg-cang-T99954-Ab-2Anti-Canine PTGIR monoclonal antibodyCanine
GM-Tg-bovg-T99954-Ab-1/ GM-Tg-bovg-T99954-Ab-2Anti-Bovine PTGIR monoclonal antibodyBovine
GM-Tg-equg-T99954-Ab-1/ GM-Tg-equg-T99954-Ab-2Anti-Equine PTGIR monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T99954-Ab-1/ GM-Tg-hg-T99954-Ab-2; GM-Tg-rg-T99954-Ab-1/ GM-Tg-rg-T99954-Ab-2;
GM-Tg-mg-T99954-Ab-1/ GM-Tg-mg-T99954-Ab-2; GM-Tg-cynog-T99954-Ab-1/ GM-Tg-cynog-T99954-Ab-2;
GM-Tg-felg-T99954-Ab-1/ GM-Tg-felg-T99954-Ab-2; GM-Tg-cang-T99954-Ab-1/ GM-Tg-cang-T99954-Ab-2;
GM-Tg-bovg-T99954-Ab-1/ GM-Tg-bovg-T99954-Ab-2; GM-Tg-equg-T99954-Ab-1/ GM-Tg-equg-T99954-Ab-2
Products NameAnti-PTGIR monoclonal antibody
Formatmab
Target NamePTGIR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PTGIR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PI2R/ PTGIR/ IP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLV000438human PTGIR Lentivirus particle
    ORF Viral VectorpGMLV000438human PTGIR Lentivirus plasmid


    Target information

    Target IDGM-T99954
    Target NamePTGIR
    Gene ID5739,19222,292661,716546,484429,101100609,520278,100071157
    Gene Symbol and SynonymsIP,PGI2,PRIPR,PTGIR
    Uniprot AccessionP43119,P43253,P79393
    Uniprot Entry NamePI2R_HUMAN,PI2R_RAT,PI2R_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000160013
    Target ClassificationGPCR

    The target: PTGIR, gene name: PTGIR, also named as IP, PRIPR. The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.