Bovine ACTH antibody and antigen (recombinant protein)

Diagnostic anti-Bovine ACTH antibodies pairs and antigen for animal health (animal Bovines/Cattle pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-ACTH-Ag01Bovine ACTH$3090.00
GMP-BOV-ACTH-Ab01Anti-Bovine ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-ACTH-Ab02Anti-Bovine ACTH mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-ACTH-Ab03Anti-Bovine ACTH human monoclonal antibody (mAb)$3090.00
GMP-BOV-ACTH-Ab04Anti-Bovine ACTH human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-ACTH-Ag01
Product NameBovine ACTH
Target/BiomarkerBovine ACTH
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine ACTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACTH level test of animal Bovines/Cattle with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
TagHis
Reconized/Reactive SpecicsBovine ACTH
Product descriptionRecombinant Bovine ACTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-ACTH-Ab01,GMP-BOV-ACTH-Ab02
Target/BiomarkerBovine ACTH
Product NameAnti-Bovine ACTH mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine ACTH antibodies in Bovine ACTH level test of animal Bovines/Cattle with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Bovine ACTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine ACTH antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-ACTH-Ab03,GMP-BOV-ACTH-Ab04
Target/BiomarkerBovine ACTH
Product NameAnti-Bovine ACTH human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine ACTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine ACTH antibodies in Bovine ACTH level test of animal Bovines/Cattle with pituitary or adrenal malfunction, pituitary tumor, adrenal tumor, lung tumor.
Product descriptionAnti-Bovine ACTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Adrenocorticotropic Hormone (ACTH) stands as a pivotal biomarker in the complex world of bovine endocrinology, serving as the conductor that orchestrates the cattle's response to stressors and maintains hormonal equilibrium. Structurally, ACTH is a 39-amino acid peptide hormone synthesized and secreted by the anterior pituitary gland. It belongs to the melanocortin family, a group of hormones with multifaceted physiological roles.

    The primary mission of ACTH lies in its regulation of the adrenal glands, specifically the adrenal cortex. When cattle encounter stressors or undergo changes in their internal environment, the hypothalamus responds by releasing corticotropin-releasing hormone (CRH). CRH, in turn, sparks the anterior pituitary gland to release ACTH into the bloodstream.

    In its journey through circulation, ACTH reaches the adrenal cortex, where it binds to specific receptors on the surface of adrenal cells. This binding event triggers intracellular processes that culminate in the synthesis and release of cortisol, a corticosteroid hormone. Commonly referred to as the "stress hormone," cortisol exerts a wide array of effects on bovine physiology.

    Cortisol takes the helm in regulating metabolism, influencing immune function, and steering the cattle's response to stressors. It elevates blood glucose levels, modulates immune responses, and orchestrates anti-inflammatory actions. Additionally, cortisol influences protein and fat metabolism, maintains electrolyte balance, and exerts its influence on cardiovascular function.



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    GDU

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