Bovine ANP antibody and antigen (recombinant protein)

Diagnostic anti-Bovine ANP antibodies pairs and antigen for animal health (animal Bovines/Cattle hypertension, cardiac hypertrophy and heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-ANP-Ag01Bovine ANP$3090.00
GMP-BOV-ANP-Ab01Anti-Bovine ANP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-ANP-Ab02Anti-Bovine ANP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-ANP-Ab03Anti-Bovine ANP human monoclonal antibody (mAb)$3090.00
GMP-BOV-ANP-Ab04Anti-Bovine ANP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-ANP-Ag01
Product NameBovine ANP
Target/BiomarkerBovine ANP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine ANP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ANP level test of animal Bovines/Cattle with hypertension, cardiac hypertrophy and heart failure.
TagHis
Reconized/Reactive SpecicsBovine ANP
Product descriptionRecombinant Bovine ANP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-ANP-Ab01,GMP-BOV-ANP-Ab02
Target/BiomarkerBovine ANP
Product NameAnti-Bovine ANP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine ANP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine ANP antibodies in Bovine ANP level test of animal Bovines/Cattle with hypertension, cardiac hypertrophy and heart failure.
Product descriptionAnti-Bovine ANP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine ANP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-ANP-Ab03,GMP-BOV-ANP-Ab04
Target/BiomarkerBovine ANP
Product NameAnti-Bovine ANP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine ANP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine ANP antibodies in Bovine ANP level test of animal Bovines/Cattle with hypertension, cardiac hypertrophy and heart failure.
Product descriptionAnti-Bovine ANP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    o delve deeper into the nature of hANP, it's essential to understand its molecular structure and physiological functions in detail. Human Atrial Natriuretic Peptide is composed of 28 amino acids, with a molecular weight of approximately 3.5 kDa. Its synthesis predominantly occurs in the cardiac atria in response to stretch receptors being activated due to increased atrial pressure or volume, a phenomenon observed during conditions such as congestive heart failure or volume expansion.Once synthesized and released into circulation, hANP exerts its effects primarily through binding to specific receptors, known as natriuretic peptide receptors (NPRs), located in various tissues, including the kidneys, blood vessels, and adrenal glands. Binding of hANP to NPRs initiates a signaling cascade that leads to vasodilation, increased glomerular filtration rate, and enhanced sodium excretion in the kidneys. These combined actions result in reduced blood volume, lower blood pressure, and maintenance of fluid and electrolyte balance.

    While the structural and functional aspects of hANP are well-conserved between humans and cattle, there may be subtle species-specific differences in the regulation of hANP expression and receptor distribution. Understanding these nuances is critical for tailoring diagnostic and therapeutic approaches in bovines effectively.



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