Bovine CBL antibody and antigen (recombinant protein)

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Diagnostic anti-Bovine CBL antibodies pairs and antigen for animal health (animal Bovines/Cattle ectopia lentis, learning difficulties and skeletal abnormalities) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Size： 1mg | 10mg | 100mg

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Validation Data

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Target/Biomarker Information

Cobalamin, or Vitamin B12, stands as a fascinating biochemically integral component within the bovine (cattle) community. This water-soluble vitamin, represented by the biomarker CBL, plays a pivotal role in an array of metabolic pathways that underpin bovine health and vitality.

Structurally, Vitamin B12 exhibits a complex molecular arrangement, with a central cobalt atom. This cobalt atom is the epicenter of Vitamin B12's biological activity, essential for its role as a coenzyme in enzymatic reactions that are foundational to bovine physiology.

One of Vitamin B12's critical roles is its involvement in the metabolic conversion of methylmalonyl-CoA to succinyl-CoA, a process catalyzed by methylmalonyl-CoA mutase. This conversion has far-reaching implications, as it contributes to the metabolism of amino acids and fatty acids, which are essential for energy production and overall cellular function in cattle. Furthermore, Vitamin B12 actively participates in the conversion of homocysteine to methionine, a reaction catalyzed by methionine synthase. Methionine is a fundamental amino acid and serves as the precursor for protein synthesis, making it indispensable for bovine growth, muscle development, and overall well-being.

Beyond these pivotal functions, Vitamin B12 is crucial for DNA synthesis in cattle. It facilitates the production of thymidine, one of the four nucleotide building blocks of DNA. This role is foundational for growth, tissue repair, and overall bovine development.

Vitamin B12's significance extends to the synthesis of myelin, the insulating sheath that envelops nerve fibers. In doing so, it ensures the efficient transmission of nerve impulses, underpinning neurological function. Additionally, Vitamin B12 plays a key role in heme synthesis, a vital component of hemoglobin within red blood cells. Hemoglobin's function in oxygen transport makes it central to bovine vitality and overall performance.

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