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Bovine PTH antibody and antigen (recombinant protein)
Diagnostic anti-Bovine PTH antibodies pairs and antigen for animal health (animal Bovines/Cattle Hyperparathyroidism) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-BOV-PTH-Ag01 | Bovine PTH | $3090.00 |
| GMP-BOV-PTH-Ab01 | Anti-Bovine PTH mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-BOV-PTH-Ab02 | Anti-Bovine PTH mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-BOV-PTH-Ab03 | Anti-Bovine PTH human monoclonal antibody (mAb) | $3090.00 |
| GMP-BOV-PTH-Ab04 | Anti-Bovine PTH human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-BOV-PTH-Ag01 |
| Product Name | Bovine PTH |
| Target/Biomarker | Bovine PTH |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Bovine PTH antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Bovines/Cattle with Hyperparathyroidism. |
| Tag | His | Reconized/Reactive Specics | Bovine PTH |
| Product description | Recombinant Bovine PTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-BOV-PTH-Ab01,GMP-BOV-PTH-Ab02 |
| Target/Biomarker | Bovine PTH |
| Product Name | Anti-Bovine PTH mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Bovine PTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PTH antibodies in Bovine PTH level test of animal Bovines/Cattle with Hyperparathyroidism. |
| Product description | Anti-Bovine PTH mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PTH antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-BOV-PTH-Ab03,GMP-BOV-PTH-Ab04 |
| Target/Biomarker | Bovine PTH |
| Product Name | Anti-Bovine PTH human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Bovine PTH antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PTH antibodies in Bovine PTH level test of animal Bovines/Cattle with Hyperparathyroidism. |
| Product description | Anti-Bovine PTH mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Parathyroid Hormone (PTH) in cattle, often referred to as bovines, stands as a remarkable biomarker central to the intricate dance of calcium and phosphorus regulation within these ruminant animals. Structurally, PTH consists of 84 amino acids and is synthesized predominantly in the parathyroid glands, four small, pea-sized structures nestled adjacent to the thyroid gland.
The fundamental role of PTH is the maintenance of calcium and phosphorus homeostasis. In response to fluctuations in serum calcium levels, PTH secretion is tightly regulated. When calcium levels plummet, PTH is swiftly released into the bloodstream, setting in motion a cascade of physiological responses designed to restore calcium balance.
One of PTH's primary actions in cattle is its stimulation of osteoclast activity. Osteoclasts are specialized bone cells responsible for resorbing bone tissue. When PTH binds to its receptors on osteoclasts, it signals these cells to break down bone matrix, releasing calcium and phosphorus into the bloodstream. This process, known as bone resorption, provides a rapid source of these minerals to meet immediate physiological demands.
Beyond bone resorption, PTH exerts its influence on renal function. It enhances the reabsorption of calcium in the renal tubules, reducing calcium loss through urine. This conserves calcium within the body. Moreover, PTH indirectly promotes calcium and phosphorus absorption from the gastrointestinal tract by stimulating the synthesis of calcitriol, the active form of vitamin D. Calcitriol, in turn, enhances the efficiency of calcium and phosphorus absorption in the intestines, ensuring a comprehensive approach to mineral balance.
PTH's significance in cattle physiology extends beyond mineral homeostasis. Adequate calcium levels are indispensable for muscle function and nerve transmission. A deficiency in calcium can lead to neuromuscular issues, affecting the ability of cattle to stand, walk, or even perform routine bodily functions. Therefore, PTH plays a pivotal role in maintaining not only skeletal health but also the overall physiological stability of bovines.
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